{"id":21217,"date":"2021-12-03T10:10:55","date_gmt":"2021-12-03T09:10:55","guid":{"rendered":"https:\/\/www.geklab.com\/predisposizioni-genetiche-il-gene-pnpla3-e-la-steatosi-epatica\/"},"modified":"2025-05-27T16:33:30","modified_gmt":"2025-05-27T15:33:30","slug":"genetic-predispositions-pnpla3-and-hepatic-steatosis","status":"publish","type":"post","link":"https:\/\/www.geklab.com\/en\/genetic-predispositions-pnpla3-and-hepatic-steatosis\/","title":{"rendered":"Genetic predispositions: the PNPLA3 gene and hepatic steatosis"},"content":{"rendered":"<figure class=\"wp-block-image alignleft size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"847\" height=\"565\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s.jpg\" alt=\"\" class=\"wp-image-8551\" style=\"width:478px;height:auto\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s.jpg 847w, https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-600x400.jpg 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-300x200.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-768x512.jpg 768w\" sizes=\"auto, (max-width: 847px) 100vw, 847px\" \/><\/figure><p><strong>Hepatic steatosis<\/strong>, also known as \u201cfatty liver,\u201d is a highly prevalent condition, including in Italy, affecting approximately <strong>25\u201330% of the adult population<\/strong> not suffering from other diseases.<\/p><p>A striking fact concerns<strong> children: 15%<\/strong> are affected by a condition of hepatic steatosis.<\/p><p>If left unmanaged, fatty liver can progress to clinically serious conditions, including <strong>liver cirrhosis <\/strong>or even <strong>liver cancer<\/strong>.<\/p><p>Human DNA contains all the information that defines each individual. Specifically, this information is encoded within genes.<\/p><p>Assessing whether one has a genetic predisposition to certain conditions, including <strong>fatty liver disease,<\/strong> makes it possible to implement dietary and supplement strategies\u2014even as a preventive measure.<\/p><blockquote class=\"wp-block-stackable-blockquote stk-block-blockquote stk-block stk-8339d85 is-style-simple\" data-v=\"2\" data-block-id=\"8339d85\"><style>.stk-8339d85{margin-bottom:0px !important}<\/style><div class=\"has-text-align-left stk-block-blockquote__content stk-container stk-8339d85-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks\"><div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-3ce51f5\" data-block-id=\"3ce51f5\"><style>.stk-3ce51f5{left:-50px !important;position:absolute !important;opacity:0.2 !important}.stk-3ce51f5 .stk--svg-wrapper .stk--inner-svg svg:last-child{height:100px !important;width:100px !important}.stk-3ce51f5 .stk--svg-wrapper .stk--inner-svg svg:last-child,.stk-3ce51f5 .stk--svg-wrapper .stk--inner-svg svg:last-child :is(g,path,rect,polygon,ellipse){fill:var(--theme-palette-color-1,#088fa8) !important}@media screen and (max-width:767px){.stk-3ce51f5{left:0px !important}}<\/style><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><linearGradient id=\"linear-gradient-3ce51f5\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-3-ce-51-f-5-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-3-ce-51-f-5-color-2)\"><\/stop><\/linearGradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 50 50\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M22.3 30.5c0 6-4.8 10.8-10.8 10.8-2.3 0-4.5-.8-6.3-2-.9-.6-1.8-1.4-2.5-2.4-1.8-2.4-2.7-5.4-2.7-9 0-4.5 1.3-8.5 4-11.9 2.7-3.4 6.4-5.8 11.1-7.3v2.8c-2.7 2.2-4.4 5-4.9 8.3.4-.1.9-.1 1.3-.1 6-.1 10.8 4.8 10.8 10.8zm16.9-10.9c-.5 0-.9 0-1.3.1.5-3.3 2.2-6.1 4.9-8.3V8.7c-4.7 1.4-8.4 3.9-11.1 7.3-2.7 3.4-4 7.4-4 11.9 0 3.6.9 6.6 2.7 9 .8 1 1.6 1.8 2.5 2.4 1.8 1.3 3.9 2 6.3 2 6 0 10.8-4.8 10.8-10.8 0-6-4.8-10.9-10.8-10.9z\"><\/path><\/svg><\/div><\/span><\/div>\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-1c8d967\" data-block-id=\"1c8d967\"><style>.stk-1c8d967 .stk-block-text__text{font-size:25px !important}@media screen and (max-width:1023px){.stk-1c8d967 .stk-block-text__text{font-size:25px !important}}<\/style><p class=\"stk-block-text__text\"><strong><span style=\"color: var(--theme-palette-color-1, #088fa8);\" class=\"stk-highlight\">The presence of a specific genetic variant (SNP) in the PNPLA3 gene is indeed associated with the development of fatty liver.<\/span><\/strong><\/p><\/div><\/div><\/div><\/blockquote><div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div><style>.kadence-column21217_46129e-9e > .kt-inside-inner-col,.kadence-column21217_46129e-9e > .kt-inside-inner-col:before{border-top-left-radius:30px;border-top-right-radius:30px;border-bottom-right-radius:30px;border-bottom-left-radius:30px;}.kadence-column21217_46129e-9e > .kt-inside-inner-col{background-color:#ebebeb;}.kadence-column21217_46129e-9e > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column21217_46129e-9e{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column21217_46129e-9e kadence-column_33b0ff-ad\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id21217_3f4a65-8b{margin-top:0px;margin-bottom:0px;}.kb-row-layout-id21217_3f4a65-8b > .kt-row-column-wrap{align-content:center;}:where(.kb-row-layout-id21217_3f4a65-8b > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:center;}.kb-row-layout-id21217_3f4a65-8b > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:0px;padding-bottom:10px;padding-left:250px;grid-template-columns:minmax(0, 80%) minmax(0, 20%);}.kb-row-layout-id21217_3f4a65-8b{background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/06\/slider4-copia-1.png');background-size:contain;background-position:3% 100%;background-attachment:scroll;background-repeat:no-repeat;}.kb-row-layout-id21217_3f4a65-8b > .kt-row-layout-overlay{opacity:0.30;}.kb-row-layout-id21217_3f4a65-8b .kt-row-layout-bottom-sep{height:100px;}.kb-row-layout-id21217_3f4a65-8b .kt-row-layout-bottom-sep svg{width:100%;}.kb-row-layout-id21217_3f4a65-8b .kt-row-layout-bottom-sep svg{fill:#ffffff!important;}@media all and (max-width: 1024px){.kb-row-layout-id21217_3f4a65-8b > .kt-row-column-wrap{padding-right:0px;padding-left:45px;grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}}@media all and (max-width: 1024px){.kb-row-layout-id21217_3f4a65-8b{background-image:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id21217_3f4a65-8b [id*=\"jarallax-container-\"]{display:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id21217_3f4a65-8b .kt-row-layout-bottom-sep{height:px;}}@media all and (max-width: 1024px){.kb-row-layout-id21217_3f4a65-8b .kt-row-layout-bottom-sep svg{width:%;}}@media all and (max-width: 767px){.kb-row-layout-id21217_3f4a65-8b > .kt-row-column-wrap{column-gap:var(--global-kb-gap-none, 0 );row-gap:var(--global-kb-gap-none, 0 );padding-top:30px;padding-right:20px;padding-bottom:20px;padding-left:20px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id21217_3f4a65-8b{background-image:none !important;}.kb-row-layout-id21217_3f4a65-8b [id*=\"jarallax-container-\"]{display:none !important;}.kb-row-layout-id21217_3f4a65-8b > .kt-row-layout-overlay{opacity:0.30;background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/09\/copertina.png');background-size:contain;background-position:right bottom;background-attachment:fixed;background-repeat:no-repeat;}.kb-row-layout-id21217_3f4a65-8b .kt-row-layout-bottom-sep{height:px;}.kb-row-layout-id21217_3f4a65-8b .kt-row-layout-bottom-sep svg{width:%;}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id21217_3f4a65-8b alignnone kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-layout-overlay kt-row-overlay-normal\"><\/div><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-equal kt-tab-layout-left-golden kt-mobile-layout-row kt-row-valign-middle\">\n<style>.kadence-column21217_d63a05-bc > .kt-inside-inner-col,.kadence-column21217_d63a05-bc > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column21217_d63a05-bc > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column21217_d63a05-bc{position:relative;}@media all and (max-width: 767px){.kadence-column21217_d63a05-bc{text-align:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column21217_d63a05-bc inner-column-1\"><div class=\"kt-inside-inner-col\"><div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<div class=\"wp-block-stackable-image stk-block-image has-text-align-left has-text-align-center-mobile stk-block stk-1fd7d15 alignleft\" data-block-id=\"1fd7d15\"><style>.stk-1fd7d15 .stk-img-wrapper{height:50px !important}.stk-1fd7d15 .stk-img-wrapper img{object-position:0% 50% !important;object-fit:contain !important}@media screen and (max-width:767px){.stk-1fd7d15{padding-right:60px !important;padding-left:60px !important}.stk-1fd7d15 .stk-img-wrapper img{object-fit:contain !important}}<\/style><a class=\"stk-link\" href=\"\/perme-test\/\"><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-19755\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program.webp\" width=\"1576\" height=\"418\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program.webp 1576w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-300x80.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-1024x272.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-768x204.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-1536x407.webp 1536w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-600x159.webp 600w\" sizes=\"auto, (max-width: 1576px) 100vw, 1576px\" \/><\/div><\/a><\/div>\n\n<div style=\"height:1px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p>Find out if you&#8217;re <strong>genetically predisposed to fatty liver disease<\/strong> with the <strong>PerM\u00e8 Medical Program.<\/strong><\/p><\/div><\/div>\n\n<style>.kadence-column21217_9dc893-53 > .kt-inside-inner-col,.kadence-column21217_9dc893-53 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column21217_9dc893-53 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column21217_9dc893-53{text-align:center;}.kadence-column21217_9dc893-53{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column21217_9dc893-53\"><div class=\"kt-inside-inner-col\"><div class=\"wp-block-stackable-image stk-block-image has-text-align-center stk-block stk-af48962\" data-block-id=\"af48962\"><style>.stk-af48962{margin-bottom:0px !important}.stk-af48962 .stk-img-wrapper{width:150px !important}<\/style><figure><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-19877\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-scaled.webp\" width=\"2560\" height=\"2560\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-scaled.webp 2560w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-300x300.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-1024x1024.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-150x150.webp 150w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-768x768.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-1536x1536.webp 1536w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-2048x2048.webp 2048w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-64x64.webp 64w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-600x600.webp 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-100x100.webp 100w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/div><\/figure><\/div>\n\n<div class=\"wp-block-stackable-button-group stk-block-button-group stk-block stk-5c8f60c\" data-block-id=\"5c8f60c\"><style>.stk-5c8f60c{padding-top:0px !important;padding-right:0px !important;padding-bottom:0px !important;padding-left:0px !important;margin-bottom:0px !important}<\/style><div class=\"stk-row stk-inner-blocks has-text-align-center stk-block-content stk-button-group\"><div class=\"wp-block-stackable-button stk-block-button has-text-align-center stk-block stk-0b72e9d\" data-block-id=\"0b72e9d\"><style>.stk-0b72e9d{margin-top:0px !important;margin-right:0px !important;margin-bottom:0px !important;margin-left:0px !important}<\/style><a class=\"stk-link stk-button stk--hover-effect-darken\" href=\"https:\/\/www.geklab.com\/en\/perme-medical-program\/\"><span class=\"stk-button__inner-text\">Find out more<\/span><\/a><\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><style>.kb-row-layout-id21217_8c4b5a-3c > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id21217_8c4b5a-3c > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id21217_8c4b5a-3c > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:0px;padding-bottom:0px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id21217_8c4b5a-3c > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id21217_8c4b5a-3c > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id21217_8c4b5a-3c > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id21217_8c4b5a-3c alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column21217_894249-60 > .kt-inside-inner-col,.kadence-column21217_894249-60 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column21217_894249-60 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column21217_894249-60{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column21217_894249-60 inner-column-1\"><div class=\"kt-inside-inner-col\"><p>It indicates a <strong>3.5-fold higher risk <\/strong>of developing fatty liver disease compared to the population without this genetic predisposition. It does not mean that the disease will certainly develop, but it helps to understand whether there is a structural, genetic factor that may facilitate its onset.<\/p>\n\n<p>Nutrition\u2014especially the personalized management of sugars and related substances\u2014plays an essential role in both prevention and treatment.<\/p>\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30667502\/\">A study published in JAMA <\/a>showed that in children who followed a diet where the intake of simple sugars was limited to 3% of daily caloric intake, diseased liver tissue was reduced from 25% to 17%. In contrast, the control group showed only a one-percentage-point reduction.<\/p>\n\n<p>Understanding if there is <strong>a genetic predisposition to fatty liver disease <\/strong>and implementing personalized dietary strategies allows one to avoid a potentially debilitating pathological condition.<\/p>\n\n<p>The <a href=\"https:\/\/www.geklab.com\/en\/perme-medical-program\/\">PerM\u00e8 Medical Program<\/a>, the <a href=\"https:\/\/www.geklab.com\/en\/glyco-medical-program\/\">Glyco Medical Program<\/a>, and the<a href=\"https:\/\/www.geklab.com\/en\/screening\/\"> screenings<\/a> allow for the analysis of any genetic predisposition to the development of fatty liver disease<\/p>\n\n<div class=\"taxonomy-post_tag wp-block-post-terms\"><a href=\"https:\/\/www.geklab.com\/en\/tag\/glyco-medical-program\/\" rel=\"tag\">Glyco Medical Program<\/a><span class=\"wp-block-post-terms__separator\">, <\/span><a href=\"https:\/\/www.geklab.com\/en\/tag\/hepatic-steatosis\/\" rel=\"tag\">hepatic steatosis<\/a><span class=\"wp-block-post-terms__separator\">, <\/span><a href=\"https:\/\/www.geklab.com\/en\/tag\/perme-medical-program\/\" rel=\"tag\">PerM\u00e8 Medical Program<\/a><span class=\"wp-block-post-terms__separator\">, <\/span><a href=\"https:\/\/www.geklab.com\/en\/tag\/pnpla3-en\/\" rel=\"tag\">PNPLA3<\/a><\/div>\n\n<p><em>A cura della <a href=\"https:\/\/www.geklab.com\/en\/the-scientific-editorial-team\/\">Redazione Scientifica GEK Lab<\/a><\/em><\/p><\/div><\/div>\n<\/div><\/div><div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-11692d3\" id=\"articoli-correlati\" data-block-id=\"11692d3\"><style>.stk-11692d3{margin-bottom:10px !important}.stk-11692d3 .stk-block-heading__text{font-size:30px !important}@media screen and (max-width:1023px){.stk-11692d3 .stk-block-heading__text{font-size:30px !important}}<\/style><h3 class=\"stk-block-heading__text has-text-align-center\">Articoli correlati<\/h3><\/div><div class=\"wp-block-uagb-post-grid uagb-post-grid  uagb-post__image-position-top uagb-post__image-enabled uagb-block-ea6d35cb     uagb-post__items uagb-post__columns-3 is-grid uagb-post__columns-tablet-2 uagb-post__columns-mobile-1 uagb-post__equal-height\" data-total=\"1\" style=\"\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"uagb-post__inner-wrap\">\t\t\t\t\t\t\t\t<div class='uagb-post__image'>\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/symptoms-sugar-inflammation\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\" class='uagb-image-ratio-inherit'><img loading=\"lazy\" decoding=\"async\" width=\"848\" height=\"565\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/04\/134001491_s.jpg\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/04\/134001491_s.jpg 848w, https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/04\/134001491_s-600x400.jpg 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/04\/134001491_s-300x200.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/04\/134001491_s-768x512.jpg 768w\" sizes=\"auto, (max-width: 848px) 100vw, 848px\" \/>\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<h5 class=\"uagb-post__title uagb-post__text\">\n\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/symptoms-sugar-inflammation\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\">The symptoms of inflammation from sugars<\/a>\n\t\t\t<\/h5>\n\t\t\t\t\t\t<div class='uagb-post__text uagb-post-grid-byline'>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class='uagb-post__text uagb-post__excerpt'>\n\t\t\t\t\tTwo specific markers\u2014glycated albumin and methylglyoxal\u2014make it possible to accurately assess an individual\u2019s inflammation status&#8230;\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Assessing whether one has a genetic predisposition to fatty liver disease allows for the implementation of dietary and supplement strategies with a preventive focus.<\/p>\n","protected":false},"author":2,"featured_media":8552,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[304],"tags":[192,389,211,410],"class_list":["post-21217","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-insights","tag-glyco-medical-program","tag-hepatic-steatosis","tag-perme-medical-program","tag-pnpla3-en"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":6}},"featured_image_urls":{"full":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s.jpg",847,565,false],"thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-150x150.jpg",150,150,true],"medium":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-300x200.jpg",300,200,true],"medium_large":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-768x512.jpg",768,512,true],"large":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s.jpg",847,565,false],"1536x1536":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s.jpg",847,565,false],"2048x2048":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s.jpg",847,565,false],"xs-thumb":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s.jpg",64,43,false],"woocommerce_archive_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-300x400.jpg",300,400,true],"woocommerce_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-300x400.jpg",300,400,true],"woocommerce_single":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-600x400.jpg",600,400,true],"woocommerce_gallery_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2021\/12\/37239059_s-100x100.jpg",50,50,true]},"post_excerpt_stackable":"<p>Assessing 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