{"id":21145,"date":"2025-04-08T13:18:22","date_gmt":"2025-04-08T12:18:22","guid":{"rendered":"https:\/\/www.geklab.com\/depressione-alimentazione-e-metabolismo\/"},"modified":"2026-04-21T09:20:38","modified_gmt":"2026-04-21T08:20:38","slug":"depression-nutrition-and-metabolism","status":"publish","type":"post","link":"https:\/\/www.geklab.com\/en\/depression-nutrition-and-metabolism\/","title":{"rendered":"Depression, nutrition, and metabolism: understanding their connections and possible solutions."},"content":{"rendered":"<div class=\"wp-block-stackable-icon-list stk-block-icon-list stk-block stk-5849285\" data-block-id=\"5849285\"><style>.stk-5849285{column-count:2 !important}.stk-5849285 ul li{list-style-image:url('data:image\/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHZpZXdCb3g9IjAgMCAxOTAgMTkwIiBzdHlsZT0iZmlsbDogIzAwMCAhaW1wb3J0YW50OyBjb2xvcjogIzAwMCAhaW1wb3J0YW50O3RyYW5zZm9ybTogcm90YXRlKGRlZykgIWltcG9ydGFudDsiPjxwb2x5Z29uIHBvaW50cz0iMTczLjgsMjguNCA2MC40LDE0MS44IDE1LjcsOTcuMiA1LjEsMTA3LjggNjAuNCwxNjMgMTg0LjQsMzkgMTczLjgsMjguNCIgZmlsbD0iIzAwMCIgc3Ryb2tlPSIjMDAwIiBzdHlsZT0iZmlsbDogcmdiKDAsIDAsIDApOyBzdHJva2U6IHJnYigwLCAwLCAwKTsiLz48L3N2Zz4=') !important}<\/style><ol><li><a href=\"#depression\">Depression and metabolism: an underestimated connection<\/a><\/li><li><a href=\"#sugar\">High blood sugar and triglycerides: how nutrition affects mood.<\/a><\/li><li><a href=\"a powerful tool against depression\">Nutrition: a powerful tool against depression<\/a><\/li><li><a href=\"#perm\u00e9\">A medical program to address inflammation and depression<\/a><\/li><li><a href=\"#conclusioni\">Prevention and treatment: the role of lifestyle<\/a><\/li><li><a href=\"#conclusioni\">Conclusion<\/a><\/li><\/ol><\/div><figure class=\"wp-block-image alignleft size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"753\" height=\"500\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5.jpg\" alt=\"\" class=\"wp-image-21095\" style=\"width:561px;height:auto\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5.jpg 753w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5-300x199.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5-600x398.jpg 600w\" sizes=\"auto, (max-width: 753px) 100vw, 753px\" \/><\/figure><p>Depression is one of the most common mental disorders in Europe, affecting approximately 5\u201310% of the population at a clinical level. Estimates indicate that <strong>more than 29 million Europeans live with depressive symptoms<\/strong>, and it is believed that around 20% of the population will experience at least one depressive episode during their lifetime. These numbers continue to rise, fueled by factors related to stress, genetics, and, above all, changes in our lifestyles and eating habits.<\/p><p>Depression, however, is not just a psychological condition: it is also closely linked to the physical body, particularly to <strong>metabolism and nutrition<\/strong>, which play a crucial role in its onset and management.<\/p><p id=\"depressione\">In this article, we will explore how these factors interact and how we can address them in an integrated way to improve our psychological well-being.<\/p><p><\/p><div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-e4812e0\" id=\"depression-and-metabolism-an-underestimated-connection\" data-block-id=\"e4812e0\"><h2 class=\"stk-block-heading__text\">Depression and metabolism: an underestimated connection<\/h2><\/div><p>Metabolism is the process by which the body converts nutrients into energy. When metabolism is disrupted, imbalances can occur that negatively affect our mental state. Metabolic disorders, such as<a href=\"https:\/\/www.geklab.com\/en\/insulin-resistance-sugar-induced-inflammation-and-weight-loss\/\"> insulin resistance<\/a>, have been closely linked to the onset of depression. <br><\/p><p><\/p><blockquote class=\"wp-block-stackable-blockquote stk-block-blockquote stk-block stk-3b473f6 is-style-default\" data-v=\"2\" data-block-id=\"3b473f6\"><div class=\"has-text-align-left stk-block-blockquote__content stk-container stk-3b473f6-container stk-hover-parent\"><div class=\"stk-block-content stk-inner-blocks\"><div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-2d67d2a\" data-block-id=\"2d67d2a\"><style>.stk-2d67d2a .stk--svg-wrapper .stk--inner-svg svg:last-child{height:88px !important;width:88px !important}<\/style><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><linearGradient id=\"linear-gradient-2d67d2a\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-2-d-67-d-2-a-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-2-d-67-d-2-a-color-2)\"><\/stop><\/linearGradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 50 50\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M22.3 30.5c0 6-4.8 10.8-10.8 10.8-2.3 0-4.5-.8-6.3-2-.9-.6-1.8-1.4-2.5-2.4-1.8-2.4-2.7-5.4-2.7-9 0-4.5 1.3-8.5 4-11.9 2.7-3.4 6.4-5.8 11.1-7.3v2.8c-2.7 2.2-4.4 5-4.9 8.3.4-.1.9-.1 1.3-.1 6-.1 10.8 4.8 10.8 10.8zm16.9-10.9c-.5 0-.9 0-1.3.1.5-3.3 2.2-6.1 4.9-8.3V8.7c-4.7 1.4-8.4 3.9-11.1 7.3-2.7 3.4-4 7.4-4 11.9 0 3.6.9 6.6 2.7 9 .8 1 1.6 1.8 2.5 2.4 1.8 1.3 3.9 2 6.3 2 6 0 10.8-4.8 10.8-10.8 0-6-4.8-10.9-10.8-10.9z\"><\/path><\/svg><\/div><\/span><\/div>\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-a5480cd\" data-block-id=\"a5480cd\"><style>.stk-a5480cd .stk-block-text__text{font-size:24px !important}@media screen and (max-width:1023px){.stk-a5480cd .stk-block-text__text{font-size:24px !important}}<\/style><p class=\"stk-block-text__text\"><strong><span style=\"color: var(--theme-palette-color-1, #088fa8)\" class=\"stk-highlight\">Depression is not just a psychological condition: it is also closely connected to the physical body, particularly to metabolism and nutrition, which play a crucial role in its onset and management.<\/span><\/strong><\/p><\/div><\/div><\/div><\/blockquote><blockquote class=\"wp-block-stackable-blockquote stk-block-blockquote stk-block stk-09d3b8f is-style-simple\" data-v=\"2\" data-block-id=\"09d3b8f\"><div class=\"has-text-align-left stk-block-blockquote__content stk-container stk-09d3b8f-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks\"><div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-65a8b24\" data-block-id=\"65a8b24\"><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><linearGradient id=\"linear-gradient-65a8b24\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-65-a-8-b-24-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-65-a-8-b-24-color-2)\"><\/stop><\/linearGradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 50 50\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M19.8 9.3C10.5 11.8 4.6 17 2.1 24.8c2.3-3.6 5.6-5.4 9.9-5.4 3.3 0 6 1.1 8.3 3.3 2.2 2.2 3.4 5 3.4 8.3 0 3.2-1.1 5.8-3.3 8-2.2 2.2-5.1 3.2-8.7 3.2-3.7 0-6.5-1.2-8.6-3.5C1 36.3 0 33.1 0 29 0 18.3 6.5 11.2 19.6 7.9l.2 1.4zm26.4 0C36.9 11.9 31 17 28.5 24.8c2.2-3.6 5.5-5.4 9.8-5.4 3.2 0 6 1.1 8.3 3.2 2.3 2.2 3.4 4.9 3.4 8.3 0 3.1-1.1 5.8-3.3 7.9-2.2 2.2-5.1 3.3-8.6 3.3-3.7 0-6.6-1.1-8.6-3.4-2.1-2.3-3.1-5.5-3.1-9.7 0-10.7 6.6-17.8 19.7-21.1l.1 1.4z\"><\/path><\/svg><\/div><\/span><\/div>\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-38c93c1\" data-block-id=\"38c93c1\"><p class=\"stk-block-text__text\">Description for this block. Use this space for describing your block. Any text will do. Description for this block. You can use this space for describing your block.<\/p><\/div><\/div><\/div><\/blockquote><style>.kadence-column21145_1e3ef8-ca > .kt-inside-inner-col,.kadence-column21145_1e3ef8-ca > .kt-inside-inner-col:before{border-top-left-radius:30px;border-top-right-radius:30px;border-bottom-right-radius:30px;border-bottom-left-radius:30px;}.kadence-column21145_1e3ef8-ca > .kt-inside-inner-col{background-color:#ebebeb;}.kadence-column21145_1e3ef8-ca > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column21145_1e3ef8-ca{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column21145_1e3ef8-ca kadence-column_33b0ff-ad\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id21145_dc7437-26{margin-top:0px;margin-bottom:0px;}.kb-row-layout-id21145_dc7437-26 > .kt-row-column-wrap{align-content:center;}:where(.kb-row-layout-id21145_dc7437-26 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:center;}.kb-row-layout-id21145_dc7437-26 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:0px;padding-bottom:10px;padding-left:250px;grid-template-columns:minmax(0, 80%) minmax(0, 20%);}.kb-row-layout-id21145_dc7437-26{background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/06\/slider4-copia-1.png');background-size:contain;background-position:3% 100%;background-attachment:scroll;background-repeat:no-repeat;}.kb-row-layout-id21145_dc7437-26 > .kt-row-layout-overlay{opacity:0.30;}.kb-row-layout-id21145_dc7437-26 .kt-row-layout-bottom-sep{height:100px;}.kb-row-layout-id21145_dc7437-26 .kt-row-layout-bottom-sep svg{width:100%;}.kb-row-layout-id21145_dc7437-26 .kt-row-layout-bottom-sep svg{fill:#ffffff!important;}@media all and (min-width: 1025px){.kb-row-layout-id21145_dc7437-26{display:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id21145_dc7437-26 > .kt-row-column-wrap{padding-right:0px;padding-left:45px;grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}}@media all and (max-width: 1024px){.kb-row-layout-id21145_dc7437-26{background-image:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id21145_dc7437-26 [id*=\"jarallax-container-\"]{display:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id21145_dc7437-26 .kt-row-layout-bottom-sep{height:px;}}@media all and (max-width: 1024px){.kb-row-layout-id21145_dc7437-26 .kt-row-layout-bottom-sep svg{width:%;}}@media all and (min-width: 768px) and (max-width: 1024px){.kb-row-layout-id21145_dc7437-26{display:none !important;}}@media all and (max-width: 767px){.kb-row-layout-id21145_dc7437-26 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-none, 0 );row-gap:var(--global-kb-gap-none, 0 );padding-top:30px;padding-right:20px;padding-bottom:20px;padding-left:20px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id21145_dc7437-26{background-image:none !important;}.kb-row-layout-id21145_dc7437-26 [id*=\"jarallax-container-\"]{display:none !important;}.kb-row-layout-id21145_dc7437-26 > .kt-row-layout-overlay{opacity:0.30;background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/09\/copertina.png');background-size:contain;background-position:right bottom;background-attachment:fixed;background-repeat:no-repeat;}.kb-row-layout-id21145_dc7437-26 .kt-row-layout-bottom-sep{height:px;}.kb-row-layout-id21145_dc7437-26 .kt-row-layout-bottom-sep svg{width:%;}.kb-row-layout-id21145_dc7437-26{display:none !important;}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id21145_dc7437-26 alignnone kb-v-lg-hidden kb-v-md-hidden kb-v-sm-hidden kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-layout-overlay kt-row-overlay-normal\"><\/div><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-equal kt-tab-layout-left-golden kt-mobile-layout-row kt-row-valign-middle\">\n<style>.kadence-column21145_58cf25-8d > .kt-inside-inner-col,.kadence-column21145_58cf25-8d > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column21145_58cf25-8d > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column21145_58cf25-8d{position:relative;}@media all and (max-width: 767px){.kadence-column21145_58cf25-8d{text-align:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column21145_58cf25-8d inner-column-1\"><div class=\"kt-inside-inner-col\"><div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<div class=\"wp-block-stackable-image stk-block-image has-text-align-left has-text-align-center-mobile stk-block stk-1fd7d15 alignleft\" data-block-id=\"1fd7d15\"><style>.stk-1fd7d15 .stk-img-wrapper{height:50px !important}.stk-1fd7d15 .stk-img-wrapper img{object-position:0% 50% !important;object-fit:contain !important}@media screen and (max-width:767px){.stk-1fd7d15{padding-right:60px !important;padding-left:60px !important}.stk-1fd7d15 .stk-img-wrapper img{object-fit:contain !important}}<\/style><a class=\"stk-link\" href=\"\/perme-test\/\"><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-19755\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program.webp\" width=\"1576\" height=\"418\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program.webp 1576w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-300x80.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-1024x272.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-768x204.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-1536x407.webp 1536w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-600x159.webp 600w\" sizes=\"auto, (max-width: 1576px) 100vw, 1576px\" \/><\/div><\/a><\/div>\n\n<div style=\"height:1px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p>Per conoscere i propri livelli di glicazione e di infiammazione e intervenire sul tono dell&#8217;umore, GEK Lab consiglia di eseguire un<strong> PerM\u00e8<\/strong> <strong>Medical Program<\/strong><\/p><\/div><\/div>\n\n<style>.kadence-column21145_d7eccb-b6 > .kt-inside-inner-col,.kadence-column21145_d7eccb-b6 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column21145_d7eccb-b6 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column21145_d7eccb-b6{text-align:center;}.kadence-column21145_d7eccb-b6{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column21145_d7eccb-b6\"><div class=\"kt-inside-inner-col\"><div class=\"wp-block-stackable-image stk-block-image has-text-align-center stk-block stk-af48962\" data-block-id=\"af48962\"><style>.stk-af48962{margin-bottom:0px !important}.stk-af48962 .stk-img-wrapper{width:150px !important}<\/style><figure><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-19877\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-scaled.webp\" width=\"2560\" height=\"2560\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-scaled.webp 2560w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-300x300.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-1024x1024.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-150x150.webp 150w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-768x768.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-1536x1536.webp 1536w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-2048x2048.webp 2048w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-64x64.webp 64w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-600x600.webp 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/perme-ita-100x100.webp 100w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/div><\/figure><\/div>\n\n<div class=\"wp-block-stackable-button-group stk-block-button-group stk-block stk-5c8f60c\" data-block-id=\"5c8f60c\"><style>.stk-5c8f60c{padding-top:0px !important;padding-right:0px !important;padding-bottom:0px !important;padding-left:0px !important;margin-bottom:0px !important}<\/style><div class=\"stk-row stk-inner-blocks has-text-align-center stk-block-content stk-button-group\"><div class=\"wp-block-stackable-button stk-block-button has-text-align-center stk-block stk-0b72e9d\" data-block-id=\"0b72e9d\"><style>.stk-0b72e9d{margin-top:0px !important;margin-right:0px !important;margin-bottom:0px !important;margin-left:0px !important}<\/style><a class=\"stk-link stk-button stk--hover-effect-darken\" href=\"https:\/\/www.geklab.com\/en\/perme-medical-program\/\"><span class=\"stk-button__inner-text\">Find out more<\/span><\/a><\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><style>.kb-row-layout-id21145_cb9b29-77 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id21145_cb9b29-77 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id21145_cb9b29-77 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id21145_cb9b29-77 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id21145_cb9b29-77 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id21145_cb9b29-77 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id21145_cb9b29-77 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column21145_2498bd-7b > .kt-inside-inner-col,.kadence-column21145_2498bd-7b > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column21145_2498bd-7b > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column21145_2498bd-7b{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column21145_2498bd-7b inner-column-1\"><div class=\"kt-inside-inner-col\"><p id=\"zuccheri\">Insulin resistance, in which the body does not respond properly to insulin, leads to<a href=\"https:\/\/www.geklab.com\/en\/diabetes-and-hyperglycemia-an-overview\/\"> a buildup of sugar in the blood<\/a>, with harmful effects not only on physical health but also on mental well-being. A study published in the <strong>Journal of Clinical Endocrinology and Metabolism<\/strong> found that the disruption of hormonal mechanisms involved in metabolism can promote the onset of depressive symptoms. Metabolism does not function solely as an energy management system, but also as a system that directly influences brain activity, altering neurotransmitters and mood.<br><\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-107c2fd\" id=\"il-digiuno-breve-come-alleato-della-chemioterapia\" data-block-id=\"107c2fd\"><style>.stk-107c2fd{margin-bottom:16px !important}<\/style><h2 class=\"stk-block-heading__text\">High blood sugar and triglycerides: how nutrition affects mood.<\/h2><\/div>\n\n<p id=\"alimentazione\">The link between high sugar levels, triglycerides, and depression is now well documented. A diet high in sugar and refined carbohydrates can cause blood sugar fluctuations, which disrupt insulin levels and negatively affect the brain&#8217;s neurotransmitter regulation of mood, promoting the development of depressive symptoms. These blood sugar swings not only weaken mood but also increase inflammation\u2014another factor that negatively impacts mental health. Studies, including those published in the <strong>Journal of Affective Disorders<\/strong>, have shown that <a href=\"https:\/\/www.geklab.com\/en\/all-due-to-inflammation\/\">chronic inflammation<\/a> can<strong> impair brain function<\/strong> by reducing the production of essential chemicals for psychological well-being, such as serotonin.<\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-dbe001e\" id=\"a-href-nutrition-a-powerful-tool-against-depression-nutrition-a-powerful-tool-against-depression-a\" data-block-id=\"dbe001e\"><style>.stk-dbe001e{margin-bottom:16px !important}<\/style><h2 class=\"stk-block-heading__text\"><a href=\"a powerful tool against depression\">Nutrition: a powerful tool against depression<\/a><\/h2><\/div>\n\n<p>A healthy diet is essential for preventing and treating depression. Certain nutrients play a key role in the <strong>production of neurotransmitters that regulate mood, such as serotonin<\/strong>, which depends on tryptophan\u2014an amino acid found in foods like turkey, pumpkin seeds, legumes, and nuts. In addition, <strong>healthy fats such as omega-3s<\/strong>, found in oily fish and walnuts, are vital for brain health, helping to reduce inflammation and improve cognitive function. <strong>Fiber, found in whole grains, vegetables, and fruits,<\/strong> is equally important as it helps maintain stable blood sugar levels, preventing glycemic spikes that can trigger mood swings and supporting a healthy gut microbiota. <\/p>\n\n<p>It\u2019s also important to know that <strong>what we eat has a direct impact on our sleep,<\/strong> which in turn deeply influences mood and mental health. Foods rich in tryptophan\u2014such as dairy products, bananas, and sesame seeds\u2014can promote the production of melatonin, the hormone that regulates the sleep-wake cycle, thereby improving sleep quality and reducing depressive symptoms. On the other hand,<strong> foods high in refined sugars and caffeine, especially when consumed in the afternoon or evening, can interfere with sleep<\/strong> and worsen depressive symptoms. <strong>Alcohol, although initially relaxing, can disrupt sleep<\/strong> and reduce sleep quality, contributing to a worsening of depressive symptoms. <\/p>\n\n<p id=\"perm\u00e9\">Finally, sleep quality depends not only on diet but also on lifestyle. It\u2019s essential to follow a regular bedtime routine and include relaxation techniques in your weekly schedule, such as meditation or yoga. Last but not least, regular physical exercise plays a key role\u2014it creates a <strong>\u201chealthy\u201d physical tiredness and boosts the production of endorphins<\/strong>, enhancing both mood and sleep quality. <\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-5832add\" id=\"per-me-a-medical-program-to-address-inflammation-and-depression\" data-block-id=\"5832add\"><style>.stk-5832add{margin-bottom:16px !important}<\/style><h2 class=\"stk-block-heading__text\">PerM\u00e9: a medical program to address inflammation and depression<\/h2><\/div>\n\n<p id=\"conclusioni\">Chronic inflammation has been identified as one of the main factors contributing to depression, as it can disrupt neurochemical processes in the brain, weakening mood regulation and causing both physical and mental fatigue that help sustain a depressive state. The <a href=\"https:\/\/www.geklab.com\/en\/product\/perme-recaller-program\/\">PerM\u00e9 Recaller program<\/a>, through a self-administered capillary blood test, provides detailed insights into how the body reacts to certain foods, revealing potential excesses and repetitive dietary patterns that may trigger inflammation.<\/p>\n\n<p id=\"prevenzione\">Once the test has been completed, <a href=\"https:\/\/www.geklab.com\/en\/diets-compared\/\">the next step is to follow the personalized diet <\/a>outlined in the medical report, with the goal of reducing inflammation, improving metabolism, restoring proper energy levels, and helping to rebalance mood\u2014potentially <strong>alongside other therapies<\/strong>. In this way, nutrition not only enhances physical health but also becomes a powerful ally in the fight against depression.<\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-6bc6313\" id=\"prevention-and-treatment-the-role-of-lifestyle\" data-block-id=\"6bc6313\"><style>.stk-6bc6313{margin-bottom:16px !important}<\/style><h2 class=\"stk-block-heading__text\">Prevention and treatment: the role of lifestyle<\/h2><\/div>\n\n<p>Depression is a disorder that requires an integrated approach. In addition to a balanced diet, it is essential to adopt a lifestyle that promotes both mental and physical well-being. <strong>Regular physical exercise<\/strong>, for example, stimulates the production of positive neurotransmitters such as endorphins and serotonin, helping to reduce depressive symptoms. Stress management through relaxation techniques like meditation, along with maintaining a healthy sleep routine, is also crucial.<\/p>\n\n<p id=\"conclusioni\">Moreover, a lifestyle that includes an <a href=\"https:\/\/www.geklab.com\/en\/anti-inflammatory-diet\/\">anti-inflammatory diet<\/a> rich in essential nutrients, quality sleep, regular physical activity, and effective stress management can make a significant difference in both the treatment and prevention of depression. Consulting a doctor or nutritionist for a personalized nutrition plan\u2014potentially supported by tests like <a href=\"https:\/\/www.geklab.com\/en\/product\/perme-recaller-program\/\">PerM\u00e9 Recaller Program<\/a>\u2014can provide concrete support in improving both psychological and physical health in a holistic way.<\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-411bdc8\" id=\"conclusion\" data-block-id=\"411bdc8\"><h2 class=\"stk-block-heading__text\">Conclusion<\/h2><\/div>\n\n<p>Depression is a complex disorder involving multiple factors. A balanced diet, healthy metabolism, and proper lifestyle are fundamental for both preventing and treating this condition. Targeted interventions\u2014such as using the <a href=\"https:\/\/www.geklab.com\/en\/product\/perme-recaller-program\/\">PerM\u00e9 Recaller program<\/a> to identify food-related inflammation and elevated glycation levels\u2014can be the first step toward improving psychological well-being through mindful and personalized dietary choices. Managing depression should not be limited to psychological or pharmacological treatments alone; it should also include a holistic approach that takes into account the role of diet and individual metabolism.<\/p>\n\n<p><\/p>\n\n<p><em>Edited by <a href=\"https:\/\/www.geklab.com\/en\/the-scientific-editorial-team\/\">The scientific editorial Team GEK Lab<\/a><\/em><\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-11692d3\" id=\"articoli-correlati\" data-block-id=\"11692d3\"><style>.stk-11692d3{margin-bottom:10px !important}.stk-11692d3 .stk-block-heading__text{font-size:30px !important}@media screen and (max-width:1023px){.stk-11692d3 .stk-block-heading__text{font-size:30px !important}}<\/style><h3 class=\"stk-block-heading__text has-text-align-center\">Articoli correlati<\/h3><\/div>\n\n<div class=\"wp-block-uagb-post-grid uagb-post-grid  uagb-post__image-position-top uagb-post__image-enabled uagb-block-ea6d35cb     uagb-post__items uagb-post__columns-3 is-grid uagb-post__columns-tablet-2 uagb-post__columns-mobile-1 uagb-post__equal-height\" data-total=\"1\" style=\"\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"uagb-post__inner-wrap\">\t\t\t\t\t\t\t\t<div class='uagb-post__image'>\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/daytime-drowsiness-causes-symptoms-and-solutions\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\" class='uagb-image-ratio-inherit'><img loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2023\/07\/Ipoglicemia-reattiva-e-diabete-due-facce-di-una-stessa-medaglia_articleimage.jpeg\" class=\"attachment-large size-large\" alt=\"Sonnolenza diurna\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2023\/07\/Ipoglicemia-reattiva-e-diabete-due-facce-di-una-stessa-medaglia_articleimage.jpeg 750w, https:\/\/www.geklab.com\/wp-content\/uploads\/2023\/07\/Ipoglicemia-reattiva-e-diabete-due-facce-di-una-stessa-medaglia_articleimage-600x400.jpeg 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2023\/07\/Ipoglicemia-reattiva-e-diabete-due-facce-di-una-stessa-medaglia_articleimage-300x200.jpeg 300w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/>\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<h5 class=\"uagb-post__title uagb-post__text\">\n\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/daytime-drowsiness-causes-symptoms-and-solutions\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\">Daytime drowsiness: causes, symptoms, and solutions<\/a>\n\t\t\t<\/h5>\n\t\t\t\t\t\t<div class='uagb-post__text uagb-post-grid-byline'>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class='uagb-post__text uagb-post__excerpt'>\n\t\t\t\t\tDaytime sleepiness is a common condition characterized by a persistent feeling of tiredness throughout the&#8230;\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"uagb-post__inner-wrap\">\t\t\t\t\t\t\t\t<div class='uagb-post__image'>\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/insulin-resistance-sugar-induced-inflammation-and-weight-loss\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\" class='uagb-image-ratio-inherit'><img loading=\"lazy\" decoding=\"async\" width=\"693\" height=\"500\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2023\/07\/Sovrappeso-infiammazione-e-alimentazione_articleimage.jpeg\" class=\"attachment-large size-large\" alt=\"Ragazza affetta da resistenza insulinica\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2023\/07\/Sovrappeso-infiammazione-e-alimentazione_articleimage.jpeg 693w, https:\/\/www.geklab.com\/wp-content\/uploads\/2023\/07\/Sovrappeso-infiammazione-e-alimentazione_articleimage-600x433.jpeg 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2023\/07\/Sovrappeso-infiammazione-e-alimentazione_articleimage-300x216.jpeg 300w\" sizes=\"auto, (max-width: 693px) 100vw, 693px\" \/>\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<h5 class=\"uagb-post__title uagb-post__text\">\n\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/insulin-resistance-sugar-induced-inflammation-and-weight-loss\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\">Insulin resistance, sugar-induced inflammation, and weight loss<\/a>\n\t\t\t<\/h5>\n\t\t\t\t\t\t<div class='uagb-post__text uagb-post-grid-byline'>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class='uagb-post__text uagb-post__excerpt'>\n\t\t\t\t\tRecognizing the symptoms of insulin resistance and adopting strategies to address it is crucial for&#8230;\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div><\/div>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Estimates indicate that more than 29 million Europeans live with depressive symptoms, and it is calculated that around 20% of the population will experience at least one depressive episode during their lifetime. These numbers continue to rise, fueled by factors related to stress, as well as changes in our lifestyles and eating habits.<\/p>\n<p>Depression is not just a psychological condition: it is also closely linked to the body, particularly metabolism and nutrition, which play a crucial role in both its onset and management.<\/p>\n","protected":false},"author":10,"featured_media":21096,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[305],"tags":[409,408,191,334,309,229,211],"class_list":["post-21145","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-conditions","tag-depression","tag-depressione-en","tag-glycation","tag-infiammazione-en","tag-inflammation-en","tag-metabolism","tag-perme-medical-program"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":6}},"featured_image_urls":{"full":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5.jpg",753,500,false],"thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5-150x150.jpg",150,150,true],"medium":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5-300x199.jpg",300,199,true],"medium_large":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5.jpg",753,500,false],"large":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5.jpg",753,500,false],"1536x1536":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5.jpg",753,500,false],"2048x2048":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5.jpg",753,500,false],"xs-thumb":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5-64x64.jpg",64,64,true],"woocommerce_archive_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5-300x400.jpg",300,400,true],"woocommerce_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5-300x400.jpg",300,400,true],"woocommerce_single":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5-600x398.jpg",600,398,true],"woocommerce_gallery_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5-64x64.jpg",50,50,true]},"post_excerpt_stackable":"<p>Estimates indicate that more than 29 million Europeans live with depressive symptoms, and it is calculated that around 20% of the population will experience at least one depressive episode during their lifetime. These numbers continue to rise, fueled by factors related to stress, as well as changes in our lifestyles and eating habits.<\/p>\n<p>Depression is not just a psychological condition: it is also closely linked to the body, particularly metabolism and nutrition, which play a crucial role in both its onset and management.<\/p>\n","category_list":"<a href=\"https:\/\/www.geklab.com\/en\/category\/conditions\/\" rel=\"category tag\">Conditions<\/a>","author_info":{"name":"Eugenio Spagnolini","url":"https:\/\/www.geklab.com\/en\/author\/eugenio\/"},"comments_num":"0 comments","yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Depression, nutrition, and metabolism: understanding their connections and possible solutions.<\/title>\n<meta name=\"description\" content=\"La depressione non \u00e8 solo una condizione psicologica: \u00e8 strettamente legata al metabolismo e all\u2019alimentazione, che giocano un ruolo cruciale nella sua insorgenza e gestione.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.geklab.com\/en\/depression-nutrition-and-metabolism\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Depression, nutrition, and metabolism: understanding their connections and possible solutions.\" \/>\n<meta property=\"og:description\" content=\"Negli ultimi anni, le ricerche scientifiche hanno sottolineato l&#039;importanza dell&#039;alimentazione nella prevenzione e nel trattamento del tumore. In particolare, l&#039;effetto degli zuccheri sullo sviluppo e sulla progressione delle malattie oncologiche ha guadagnato attenzione.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.geklab.com\/en\/depression-nutrition-and-metabolism\/\" \/>\n<meta property=\"og:site_name\" content=\"GEK Lab\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/geklab.official\" \/>\n<meta property=\"article:published_time\" content=\"2025-04-08T12:18:22+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-21T08:20:38+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Depressione-come-affrontarla-naturalmente_articleimage-5.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"753\" \/>\n\t<meta property=\"og:image:height\" content=\"500\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Eugenio Spagnolini\" \/>\n<meta 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