{"id":19032,"date":"2020-04-17T12:41:00","date_gmt":"2020-04-17T11:41:00","guid":{"rendered":"https:\/\/www.geklab.com\/infiammazione-da-alimenti\/"},"modified":"2026-04-23T16:04:17","modified_gmt":"2026-04-23T15:04:17","slug":"food-related-inflammation-and-great-food-groups","status":"publish","type":"post","link":"https:\/\/www.geklab.com\/en\/food-related-inflammation-and-great-food-groups\/","title":{"rendered":"Food-related inflammation and great food groups"},"content":{"rendered":"<div class=\"wp-block-stackable-icon-list stk-block-icon-list stk-block stk-d8dbfc0\" data-block-id=\"d8dbfc0\"><style>.stk-d8dbfc0{margin-bottom:37px !important;column-count:2 !important}.stk-d8dbfc0 ul li{list-style-image:url('data:image\/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHZpZXdCb3g9IjAgMCAxOTAgMTkwIiBzdHlsZT0iZmlsbDogIzAwMCAhaW1wb3J0YW50OyBjb2xvcjogIzAwMCAhaW1wb3J0YW50O3RyYW5zZm9ybTogcm90YXRlKGRlZykgIWltcG9ydGFudDsiPjxwb2x5Z29uIHBvaW50cz0iMTczLjgsMjguNCA2MC40LDE0MS44IDE1LjcsOTcuMiA1LjEsMTA3LjggNjAuNCwxNjMgMTg0LjQsMzkgMTczLjgsMjguNCIgZmlsbD0iIzAwMCIgc3Ryb2tlPSIjMDAwIiBzdHlsZT0iZmlsbDogcmdiKDAsIDAsIDApOyBzdHJva2U6IHJnYigwLCAwLCAwKTsiLz48L3N2Zz4=') !important}<\/style><ol><li><a href=\"#BAFF\">BAFF (B-Cell Activating Factor) <\/a><\/li><li><a href=\"#allergy\">Allergy, intolerance and food-related inflammation: comparative concepts<\/a><\/li><li><a href=\"#role\">Role of IgE and IgG<\/a><\/li><li><span style=\"color: var(--theme-palette-color-1, #088fa8)\" class=\"stk-highlight\"><a href=\"#great\">The great food groups<\/a><\/span><\/li><\/ol><\/div><figure class=\"wp-block-image alignleft size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4.jpg\" alt=\"\" class=\"wp-image-17064\" style=\"width:520px;height:auto\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4.jpg 750w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4-300x200.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4-600x400.jpg 600w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/><\/figure><p id=\"BAFF\">For a long time, <strong>ESR<\/strong> (Erythrocyte Sedimentation Rate) and <strong>CRP<\/strong> (C-Reactive Protein) have been the primary biomarkers for assessing inflammation. <\/p><p id=\"BAFF\">ESR indicates the overall inflammatory state, while CRP is produced by the liver in response to inflammation or infection. <\/p><p id=\"BAFF\">However, these &#8220;acute-phase&#8221; proteins have limitations in specificity and sensitivity for identifying <strong>low-grade inflammation<\/strong>. <\/p><p id=\"BAFF\">Other biomarkers related to specific immune pathways are more accurate for this type of inflammation.<\/p><div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-a9be0f8\" id=\"strong-baff-strong-strong-b-cell-activating-factor-strong\" data-block-id=\"a9be0f8\"><style>.stk-a9be0f8{margin-bottom:15px !important}<\/style><h2 class=\"stk-block-heading__text\"><strong>BAFF<\/strong> <strong>(B-Cell Activating Factor)<\/strong><\/h2><\/div><p><a href=\"https:\/\/www.geklab.com\/en\/baff-a-multitasking-molecule-why-measure-it-and-how-to-deal-with-it\/\">BAFF<\/a> is a new biomarker of inflammation related to immune contact with food.<\/p><p><strong>BAFF<\/strong> is a protein involved in inflammation, produced by various immune system cells (such as macrophages and T cells), as well as by adipose tissue and epithelial cells in the respiratory tract.<\/p><blockquote class=\"wp-block-stackable-blockquote stk-block-blockquote stk-block stk-1af1c7d is-style-simple\" data-v=\"2\" data-block-id=\"1af1c7d\"><div class=\"has-text-align-left stk-block-blockquote__content stk-container stk-1af1c7d-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks\"><div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-032b376\" data-block-id=\"032b376\"><style>.stk-032b376{top:-50px !important;left:-50px !important;position:absolute !important;opacity:0.2 !important}.stk-032b376 .stk--svg-wrapper .stk--inner-svg svg:last-child{height:200px !important;width:200px !important}.stk-032b376 .stk--svg-wrapper .stk--inner-svg svg:last-child,.stk-032b376 .stk--svg-wrapper .stk--inner-svg svg:last-child :is(g,path,rect,polygon,ellipse){fill:var(--theme-palette-color-1,#088fa8) !important}<\/style><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><linearGradient id=\"linear-gradient-032b376\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-032-b-376-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-032-b-376-color-2)\"><\/stop><\/linearGradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 50 50\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M22.3 30.5c0 6-4.8 10.8-10.8 10.8-2.3 0-4.5-.8-6.3-2-.9-.6-1.8-1.4-2.5-2.4-1.8-2.4-2.7-5.4-2.7-9 0-4.5 1.3-8.5 4-11.9 2.7-3.4 6.4-5.8 11.1-7.3v2.8c-2.7 2.2-4.4 5-4.9 8.3.4-.1.9-.1 1.3-.1 6-.1 10.8 4.8 10.8 10.8zm16.9-10.9c-.5 0-.9 0-1.3.1.5-3.3 2.2-6.1 4.9-8.3V8.7c-4.7 1.4-8.4 3.9-11.1 7.3-2.7 3.4-4 7.4-4 11.9 0 3.6.9 6.6 2.7 9 .8 1 1.6 1.8 2.5 2.4 1.8 1.3 3.9 2 6.3 2 6 0 10.8-4.8 10.8-10.8 0-6-4.8-10.9-10.8-10.9z\"><\/path><\/svg><\/div><\/span><\/div>\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-523c857\" data-block-id=\"523c857\"><style>.stk-523c857 .stk-block-text__text{font-size:25px !important}@media screen and (max-width:1023px){.stk-523c857 .stk-block-text__text{font-size:25px !important}}<\/style><p class=\"stk-block-text__text\"><strong><span style=\"color: var(--theme-palette-color-1, #088fa8)\" class=\"stk-highlight\">The term &#8220;food intolerance&#8221; has been widely misunderstood and has often led to the dangerous elimination of foods from the diet, based on specific symptoms or on unscientific &#8220;food intolerance&#8221; tests.<\/span><\/strong><\/p><\/div><\/div><\/div><\/blockquote><style>.kadence-column19032_0497e2-92 > .kt-inside-inner-col,.kadence-column19032_0497e2-92 > .kt-inside-inner-col:before{border-top-left-radius:30px;border-top-right-radius:30px;border-bottom-right-radius:30px;border-bottom-left-radius:30px;}.kadence-column19032_0497e2-92 > .kt-inside-inner-col{background-color:#ebebeb;}.kadence-column19032_0497e2-92 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column19032_0497e2-92{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column19032_0497e2-92 kadence-column_33b0ff-ad\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id19032_74d276-e7{margin-top:0px;margin-bottom:0px;}.kb-row-layout-id19032_74d276-e7 > .kt-row-column-wrap{align-content:center;}:where(.kb-row-layout-id19032_74d276-e7 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:center;}.kb-row-layout-id19032_74d276-e7 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:0px;padding-bottom:10px;padding-left:250px;grid-template-columns:minmax(0, 80%) minmax(0, 20%);}.kb-row-layout-id19032_74d276-e7{background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/02\/slider2-copia.png');background-size:contain;background-position:3% 100%;background-attachment:scroll;background-repeat:no-repeat;}.kb-row-layout-id19032_74d276-e7 > .kt-row-layout-overlay{opacity:0.30;}.kb-row-layout-id19032_74d276-e7 .kt-row-layout-bottom-sep{height:100px;}.kb-row-layout-id19032_74d276-e7 .kt-row-layout-bottom-sep svg{width:100%;}.kb-row-layout-id19032_74d276-e7 .kt-row-layout-bottom-sep svg{fill:#ffffff!important;}@media all and (min-width: 1025px){.kb-row-layout-id19032_74d276-e7{display:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id19032_74d276-e7 > .kt-row-column-wrap{padding-right:0px;padding-left:45px;grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}}@media all and (max-width: 1024px){.kb-row-layout-id19032_74d276-e7{background-image:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id19032_74d276-e7 [id*=\"jarallax-container-\"]{display:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id19032_74d276-e7 .kt-row-layout-bottom-sep{height:px;}}@media all and (max-width: 1024px){.kb-row-layout-id19032_74d276-e7 .kt-row-layout-bottom-sep svg{width:%;}}@media all and (min-width: 768px) and (max-width: 1024px){.kb-row-layout-id19032_74d276-e7{display:none !important;}}@media all and (max-width: 767px){.kb-row-layout-id19032_74d276-e7 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-none, 0 );row-gap:var(--global-kb-gap-none, 0 );padding-top:30px;padding-right:20px;padding-bottom:20px;padding-left:20px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id19032_74d276-e7{background-image:none !important;}.kb-row-layout-id19032_74d276-e7 [id*=\"jarallax-container-\"]{display:none !important;}.kb-row-layout-id19032_74d276-e7 > .kt-row-layout-overlay{opacity:0.30;background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/09\/copertina.png');background-size:contain;background-position:right bottom;background-attachment:fixed;background-repeat:no-repeat;}.kb-row-layout-id19032_74d276-e7 .kt-row-layout-bottom-sep{height:px;}.kb-row-layout-id19032_74d276-e7 .kt-row-layout-bottom-sep svg{width:%;}.kb-row-layout-id19032_74d276-e7{display:none !important;}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id19032_74d276-e7 alignnone kb-v-lg-hidden kb-v-md-hidden kb-v-sm-hidden kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-layout-overlay kt-row-overlay-normal\"><\/div><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-equal kt-tab-layout-left-golden kt-mobile-layout-row kt-row-valign-middle\">\n<style>.kadence-column19032_a9679f-26 > .kt-inside-inner-col,.kadence-column19032_a9679f-26 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column19032_a9679f-26 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column19032_a9679f-26{position:relative;}@media all and (max-width: 767px){.kadence-column19032_a9679f-26{text-align:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column19032_a9679f-26 inner-column-1\"><div class=\"kt-inside-inner-col\"><div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<div class=\"wp-block-stackable-image stk-block-image has-text-align-left has-text-align-center-mobile stk-block stk-1fd7d15 alignleft\" data-block-id=\"1fd7d15\"><style>.stk-1fd7d15 .stk-img-wrapper{height:50px !important}.stk-1fd7d15 .stk-img-wrapper img{object-position:0% 50% !important;object-fit:contain !important}@media screen and (max-width:767px){.stk-1fd7d15{padding-right:60px !important;padding-left:60px !important}.stk-1fd7d15 .stk-img-wrapper img{object-fit:contain !important}}<\/style><a class=\"stk-link\" href=\"\/perme-test\/\"><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-19761\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Recaller_medical_program.webp\" width=\"1880\" height=\"410\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Recaller_medical_program.webp 1880w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Recaller_medical_program-300x65.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Recaller_medical_program-1024x223.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Recaller_medical_program-768x167.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Recaller_medical_program-1536x335.webp 1536w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Recaller_medical_program-600x131.webp 600w\" sizes=\"auto, (max-width: 1880px) 100vw, 1880px\" \/><\/div><\/a><\/div>\n\n<div style=\"height:1px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p>To assess food-related inflammation and bring symptoms under control, we recommend taking a <strong>Recaller<\/strong> <strong>Medical Program<\/strong><\/p><\/div><\/div>\n\n<style>.kadence-column19032_9c56e5-4c > .kt-inside-inner-col,.kadence-column19032_9c56e5-4c > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column19032_9c56e5-4c > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column19032_9c56e5-4c{text-align:center;}.kadence-column19032_9c56e5-4c{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column19032_9c56e5-4c\"><div class=\"kt-inside-inner-col\"><div class=\"wp-block-stackable-image stk-block-image has-text-align-center stk-block stk-af48962\" data-block-id=\"af48962\"><style>.stk-af48962{margin-bottom:0px !important}.stk-af48962 .stk-img-wrapper{width:150px !important}<\/style><figure><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-19898\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-scaled.webp\" width=\"2560\" height=\"2560\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-scaled.webp 2560w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-300x300.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-1024x1024.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-150x150.webp 150w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-768x768.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-1536x1536.webp 1536w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-2048x2048.webp 2048w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-64x64.webp 64w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-600x600.webp 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/recaller-eng-100x100.webp 100w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/div><\/figure><\/div>\n\n<div class=\"wp-block-stackable-button-group stk-block-button-group stk-block stk-5c8f60c\" data-block-id=\"5c8f60c\"><style>.stk-5c8f60c{padding-top:0px !important;padding-right:0px !important;padding-bottom:0px !important;padding-left:0px !important;margin-bottom:0px !important}<\/style><div class=\"stk-row stk-inner-blocks has-text-align-center stk-block-content stk-button-group\"><div class=\"wp-block-stackable-button stk-block-button has-text-align-center stk-block stk-0b72e9d\" data-block-id=\"0b72e9d\"><style>.stk-0b72e9d{margin-top:0px !important;margin-right:0px !important;margin-bottom:0px !important;margin-left:0px !important}<\/style><a class=\"stk-link stk-button stk--hover-effect-darken\" href=\"https:\/\/www.geklab.com\/en\/recaller-medical-program\/\"><span class=\"stk-button__inner-text\">See more<\/span><\/a><\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><p id=\"Allergia\">BAFF can be used as &#8220;thermometer&#8221; to assess the extent of systemic inflammation, including that related to food. Its level rises in response to external and internal stimuli, <strong>contributing to inflammatory conditions and autoimmune diseases<\/strong>. Although BAFF is not an exclusive marker of food reactions, <strong>It is influenced by diet<\/strong> and can be used to implement nutritional adjustments and evaluate the need for further diagnostic investigations.<\/p><div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-0bf55ec\" id=\"allergy\" data-block-id=\"0bf55ec\"><style>.stk-0bf55ec{margin-bottom:14px !important}<\/style><h2 class=\"stk-block-heading__text\"><strong>Allergy, intolerance, and food-related inflammation: comparative concepts<\/strong><\/h2><\/div><p>In 2017, the&nbsp;<em><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28445677\/\" target=\"_blank\" rel=\"noreferrer noopener\">New England Journal of Medicine<\/a><\/em>&nbsp;confirmed the correlation between BAFF and the development or maintenance of autoimmune diseases, thus opening new possibilities for diagnosis and treatment.<\/p><p>The <strong>TNFSF13B gene<\/strong> was identified as responsible for the synthesis of BAFF, and a genetic variant, BAFF-var, has been associated with an <strong>increased risk of autoimmunity<\/strong>. However, this variant only accounts for a portion (24-27%) of cases of elevated BAFF levels, with the majority being attributed to environmental factors, including diet. The presence of BAFF-var is found in a variable percentage of the population, with a higher incidence in certain regions like Italy and Spain.<\/p><p>This predisposition, which can be assessed through the <a href=\"https:\/\/www.geklab.com\/en\/product\/perme-recaller-program\/\">PerM\u00e8 Recaller Program<\/a>, should be managed by activating more suitable epigenetic mechanisms (lifestyle, diet, and personalized supplementation).<\/p><p>Food allergies, food intolerances, and food-related inflammation are distinct concepts that are often confused. The only food intolerances recognized by the scientific community are <strong>celiac disease<\/strong> and <strong>lactose intolerance<\/strong>, both of which are irreversible. Additionally, lactose intolerance is dose-dependent and does not involve the immune system.<\/p><p>The term &#8220;food intolerance&#8221; has been widely misinterpreted and has often led to the <strong>dangerous elimination of foods from the diet<\/strong>, based on specific symptoms or unscientific &#8220;food intolerance&#8221; tests. What often follows is the exclusion (even temporarily) of specific foods from the diet, which fosters aspects of malnutrition, dietary inadequacy (especially in young people), and can lead to <strong>strong immune-mediated reactions<\/strong> upon reintroducing those foods.<\/p><div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-6f5b380\" id=\"role\" data-block-id=\"6f5b380\"><style>.stk-6f5b380{margin-bottom:15px !important}<\/style><h2 class=\"stk-block-heading__text\"><strong>Role of IgE and IgG<\/strong><\/h2><\/div><p><strong>Immunoglobulins E (IgE)<\/strong> are antibodies produced in response to contact with food and bind to receptors on the surface of mast cells. Mast cells are a type of white blood cell found in connective tissues and mucous membranes. When this happens, a series of events are triggered that lead to the release of inflammatory mediators such as histamine and TNF-alpha. These mediators cause an <strong>inflammatory response<\/strong>, usually manifesting within a few hours of consuming a particular food.<\/p><p><strong>Immunoglobulins G (IgG)<\/strong> are also a type of antibody produced by the immune system in response to exposure to various antigens, such as food antigens, pathogens, and toxins, and play a key role in defending the body against infections, contributing, among other things, to our <strong>immune memory<\/strong>.<\/p><p>The interaction between IgG, IgE, and food antigens depends on the relative concentration of these three elements, and depending on the situation, can provoke different responses from the body. Specifically, when IgG antibodies are present in excess compared to antigen levels, they &#8220;intercept&#8221; the antigen and block its binding to IgE. However, the antigen-IgG complexes created in this way can bind to other immune cells and trigger an IgG-mediated response.<\/p><p>IgG antibodies against foods are typically produced by the body when it comes into contact with food, and their levels increase proportionally with repeated exposure to the same category of food.<\/p><p>According to the model described above, a high number of &#8220;encounters&#8221; between antigen-antibodies of IgG, due to the repeated intake of the same food stimulus, promotes low-grade inflammation by activating an immune response mediated by this class of antibodies.<\/p><p>Many studies have described a correlation between IgG and inflammatory conditions such as <strong>Crohn\u2019s disease<\/strong>, <strong><a href=\"https:\/\/www.geklab.com\/en\/irritable-bowel-syndrome-dietary-intervention\/\">irritable bowel syndrome<\/a><\/strong> (IBS), and <strong>non-celiac gluten sensitivity<\/strong> (NCGS). All of these studies have shown that an appropriate therapeutic intervention can improve symptoms, highlighting the clinical relevance of IgG in determining delayed reactions involving IgG, macrophages, PAF, and BAFF. This was also demonstrated in a <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33292297\/\" target=\"_blank\" rel=\"noreferrer noopener\">scientific study conducted by our team<\/a>, where adherence to a specific diet was correlated with a reduction in IgG levels. Through the <a href=\"https:\/\/www.geklab.com\/en\/product\/food-recaller-program\/\">Food Recaller Program<\/a>, it is possible to obtain a comprehensive overview of an individual\u2019s relationship with food-related inflammation and IgG.<\/p><h2 class=\"wp-block-heading\" id=\"great\"><strong>The great food groups<\/strong><\/h2><figure class=\"wp-block-image alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"643\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/grandi-gruppi-1024x643.png\" alt=\"\" class=\"wp-image-17073\" style=\"width:802px;height:auto\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/grandi-gruppi-1024x643.png 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/grandi-gruppi-300x188.png 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/grandi-gruppi-768x482.png 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/grandi-gruppi-600x376.png 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/grandi-gruppi.png 1455w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Relevant food groups for the European population<\/figcaption><\/figure><p>IgG antibodies are a class of antibodies with highly variable structure and form. Their low antigen affinity means that they do not recognize a single food antigen with extreme specificity but instead recognize common antigens found in one or more food classes that share similar protein structures. <\/p><p>This has been confirmed both by various studies on the structure and function of this specific class of antibodies and by statistical studies that have allowed researchers to examine the distribution of food-specific IgG immunoglobulins in the Italian-European population.<\/p><p>Based on this &#8220;immunological similarity,&#8221; foods are classified into five major groups:<\/p><p><strong>Wheat and gluten:<\/strong>&nbsp;this group includes gluten-containing cereals such as wheat, Kamut, spelt, barley, rye, and all their derivatives. It also includes preparations containing gluten, such as soy sauce, beer, barley coffee, and so on.<\/p><p><strong>Nickel:<\/strong>&nbsp;this group includes foods such as tomatoes, spinach, oats, mushrooms, cocoa, and foods preserved in cans, such as canned tuna, canned sardines, etc.<\/p><p><strong>Yeasts and fermented products:<\/strong>&nbsp;this group includes vinegar, alcoholic beverages such as wine and beer, mushrooms, cheeses, baked goods with or without yeast, industrial citric acid (E330), soy sauce, yogurt, industrial mayonnaise, honey, etc.<\/p><p><strong>Milk and beef:<\/strong>&nbsp;this group includes milk and dairy products (yogurt and cheese), as well as beef and beef derivatives, such as bresaola (lactose intolerance, which is a sugar-related enzymatic condition, has nothing to do with the inflammation associated with the milk group).<\/p><p><strong>Cooked oils:<\/strong>&nbsp;all foods containing cooked vegetable oils, such as cookies, rusks, crackers, flatbreads, chips, roasted nuts, saut\u00e9ed foods, and fried foods.<\/p><p><em><em><em>By the&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/the-scientific-editorial-team\/\">Scientific Editorial Team at GEK Lab<\/a><\/em><\/em><\/em><\/p><div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-11692d3\" id=\"related-articles\" data-block-id=\"11692d3\"><style>.stk-11692d3{margin-bottom:10px !important}.stk-11692d3 .stk-block-heading__text{font-size:30px !important}@media screen and (max-width:1023px){.stk-11692d3 .stk-block-heading__text{font-size:30px !important}}<\/style><h3 class=\"stk-block-heading__text has-text-align-center\">Related articles<\/h3><\/div><div class=\"wp-block-uagb-post-grid uagb-post-grid  uagb-post__image-position-top uagb-post__image-enabled uagb-block-ea6d35cb     uagb-post__items uagb-post__columns-3 is-grid uagb-post__columns-tablet-2 uagb-post__columns-mobile-1 uagb-post__equal-height\" data-total=\"5\" style=\"\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"uagb-post__inner-wrap\">\t\t\t\t\t\t\t\t<div class='uagb-post__image'>\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/histamine\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\" class='uagb-image-ratio-inherit'><img loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Istamina-e-alimentazione_articleimage-4.jpg\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Istamina-e-alimentazione_articleimage-4.jpg 750w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Istamina-e-alimentazione_articleimage-4-300x200.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/04\/Istamina-e-alimentazione_articleimage-4-600x400.jpg 600w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/>\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<h5 class=\"uagb-post__title uagb-post__text\">\n\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/histamine\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\">Histamine Accumulation Syndrome: Causes, Symptoms, and the Correct Approach<\/a>\n\t\t\t<\/h5>\n\t\t\t\t\t\t<div class='uagb-post__text uagb-post-grid-byline'>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class='uagb-post__text uagb-post__excerpt'>\n\t\t\t\t\tHistamine accumulation syndrome is sometimes improperly referred to as \u201chistamine intolerance.\u201d Although this term is&#8230;\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"uagb-post__inner-wrap\">\t\t\t\t\t\t\t\t<div class='uagb-post__image'>\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/diabetic-foot\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\" class='uagb-image-ratio-inherit'><img loading=\"lazy\" decoding=\"async\" width=\"755\" height=\"500\" 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noreferrer\">Diabetic foot: when diabetes has taken too much of a foothold<\/a>\n\t\t\t<\/h5>\n\t\t\t\t\t\t<div class='uagb-post__text uagb-post-grid-byline'>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class='uagb-post__text uagb-post__excerpt'>\n\t\t\t\t\tDiabetic foot is one of the most common chronic complications of diabetes mellitus. It involves&#8230;\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"uagb-post__inner-wrap\">\t\t\t\t\t\t\t\t<div class='uagb-post__image'>\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/high-blood-pressure-and-chronic-inflammation-how-they-interact-and-how-to-intervene\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\" class='uagb-image-ratio-inherit'><img loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/10\/Ipertensione-meglio-ridurre-l-infiammazione_articleimage-5.jpg\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/10\/Ipertensione-meglio-ridurre-l-infiammazione_articleimage-5.jpg 750w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/10\/Ipertensione-meglio-ridurre-l-infiammazione_articleimage-5-300x200.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/10\/Ipertensione-meglio-ridurre-l-infiammazione_articleimage-5-600x400.jpg 600w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/>\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<h5 class=\"uagb-post__title uagb-post__text\">\n\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/high-blood-pressure-and-chronic-inflammation-how-they-interact-and-how-to-intervene\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\">High blood pressure and chronic inflammation: how they interact and how to intervene<\/a>\n\t\t\t<\/h5>\n\t\t\t\t\t\t<div class='uagb-post__text uagb-post-grid-byline'>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class='uagb-post__text uagb-post__excerpt'>\n\t\t\t\t\tHypertension, commonly referred to as &#8220;high blood pressure,&#8221; is one of the most widespread and&#8230;\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>For a long time, ESR and CRP have been the primary biomarkers for assessing inflammation. However, these &#8220;acute-phase&#8221; proteins have limitations in specificity and sensitivity for identifying low-grade inflammation. Other biomarkers, such as BAFF and PAF, which are linked to specific immune pathways, are more accurate for this type of inflammation.<\/p>\n","protected":false},"author":10,"featured_media":17065,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[304],"tags":[185,198,334,309,184,211],"class_list":["post-19032","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-insights","tag-baff-en","tag-cytokines","tag-infiammazione-en","tag-inflammation-en","tag-paf-en","tag-perme-medical-program"],"blocksy_meta":[],"featured_image_urls":{"full":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4.jpg",750,500,false],"thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4-150x150.jpg",150,150,true],"medium":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4-300x200.jpg",300,200,true],"medium_large":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4.jpg",750,500,false],"large":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4.jpg",750,500,false],"1536x1536":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4.jpg",750,500,false],"2048x2048":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4.jpg",750,500,false],"xs-thumb":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4.jpg",64,43,false],"woocommerce_archive_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4-300x400.jpg",300,400,true],"woocommerce_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4-300x400.jpg",300,400,true],"woocommerce_single":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4-600x400.jpg",600,400,true],"woocommerce_gallery_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/05\/Varieta-alimentare-uno-strumento-per-modulare-il-sistema-immunitario-controllare-le-allergie-e-l-infiammazione-da-cibo_articleimage-4-100x100.jpg",50,50,true]},"post_excerpt_stackable":"<p>For a long time, ESR and CRP have been the primary biomarkers for assessing inflammation. However, these &#8220;acute-phase&#8221; proteins have limitations in specificity and sensitivity for identifying low-grade inflammation. Other biomarkers, such as BAFF and PAF, which are linked to specific immune pathways, are more accurate for this type of inflammation.<\/p>\n","category_list":"<a href=\"https:\/\/www.geklab.com\/en\/category\/scientific-insights\/\" rel=\"category tag\">Scientific Insights<\/a>","author_info":{"name":"Eugenio Spagnolini","url":"https:\/\/www.geklab.com\/en\/author\/eugenio\/"},"comments_num":"0 comments","yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Food-related inflammation and great food groups<\/title>\n<meta name=\"description\" content=\"Food-related inflammation, food allergies, and food intolerances are distinct concepts that are often confused.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.geklab.com\/en\/food-related-inflammation-and-great-food-groups\/\" \/>\n<meta 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