{"id":17349,"date":"2022-05-05T09:23:32","date_gmt":"2022-05-05T08:23:32","guid":{"rendered":"https:\/\/www.geklab.com\/metilgliossale-un-nuovo-marcatore-di-variabilita-glicemica\/"},"modified":"2026-04-22T10:38:29","modified_gmt":"2026-04-22T09:38:29","slug":"methylglyoxal-a-new-marker-of-glycemic-variability","status":"publish","type":"post","link":"https:\/\/www.geklab.com\/en\/methylglyoxal-a-new-marker-of-glycemic-variability\/","title":{"rendered":"Methylglyoxal: a new marker of glycemic variability"},"content":{"rendered":"<figure class=\"wp-block-image alignleft size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"848\" height=\"565\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/05\/128250788_s.jpg\" alt=\"\" class=\"wp-image-8623\" style=\"width:486px;height:auto\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/05\/128250788_s.jpg 848w, https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/05\/128250788_s-600x400.jpg 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/05\/128250788_s-300x200.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/05\/128250788_s-768x512.jpg 768w\" sizes=\"auto, (max-width: 848px) 100vw, 848px\" \/><\/figure><p>Until a few years ago, the primary indicators used to detect <strong>alterations in sugar sensitivity<\/strong> were <strong>glycated hemoglobin<\/strong> (HbA1c) and <strong>fasting blood glucose levels<\/strong>.<\/p><p>However, these indicators, although very useful for controlling and monitoring an already established diabetic condition, need to be supplemented with new and innovative markers of sugar-induced damage.<\/p><p>Several scientific studies published between 2018 and 2019 in some of the most important diabetology journals have highlighted the limitations of HbA1c and fasting blood glucose in the early identification of <strong>sugar-induced damage<\/strong><sup>1,2,3<\/sup>.<\/p><p>A new marker to consider is <strong>methylglyoxal<\/strong>.<\/p><p>Methylglyoxal allows for the measurement of <strong>glycemic variability<\/strong>, which refers to the <strong>continuous fluctuations in glucose levels<\/strong> that can occur throughout the day.<\/p><blockquote class=\"wp-block-stackable-blockquote stk-block-blockquote stk-block stk-8339d85 is-style-simple\" data-v=\"2\" data-block-id=\"8339d85\"><style>.stk-8339d85{margin-bottom:0px !important}<\/style><div class=\"has-text-align-left stk-block-blockquote__content stk-container stk-8339d85-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks\"><div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-3ce51f5\" data-block-id=\"3ce51f5\"><style>.stk-3ce51f5{left:-50px !important;position:absolute !important;opacity:0.2 !important}.stk-3ce51f5 .stk--svg-wrapper .stk--inner-svg svg:last-child{height:100px !important;width:100px !important}.stk-3ce51f5 .stk--svg-wrapper .stk--inner-svg svg:last-child,.stk-3ce51f5 .stk--svg-wrapper .stk--inner-svg svg:last-child :is(g,path,rect,polygon,ellipse){fill:var(--theme-palette-color-1,#088fa8) !important}@media screen and (max-width:767px){.stk-3ce51f5{left:0px !important}}<\/style><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><linearGradient id=\"linear-gradient-3ce51f5\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-3-ce-51-f-5-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-3-ce-51-f-5-color-2)\"><\/stop><\/linearGradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 50 50\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M22.3 30.5c0 6-4.8 10.8-10.8 10.8-2.3 0-4.5-.8-6.3-2-.9-.6-1.8-1.4-2.5-2.4-1.8-2.4-2.7-5.4-2.7-9 0-4.5 1.3-8.5 4-11.9 2.7-3.4 6.4-5.8 11.1-7.3v2.8c-2.7 2.2-4.4 5-4.9 8.3.4-.1.9-.1 1.3-.1 6-.1 10.8 4.8 10.8 10.8zm16.9-10.9c-.5 0-.9 0-1.3.1.5-3.3 2.2-6.1 4.9-8.3V8.7c-4.7 1.4-8.4 3.9-11.1 7.3-2.7 3.4-4 7.4-4 11.9 0 3.6.9 6.6 2.7 9 .8 1 1.6 1.8 2.5 2.4 1.8 1.3 3.9 2 6.3 2 6 0 10.8-4.8 10.8-10.8 0-6-4.8-10.9-10.8-10.9z\"><\/path><\/svg><\/div><\/span><\/div>\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-1c8d967\" data-block-id=\"1c8d967\"><style>.stk-1c8d967 .stk-block-text__text{font-size:25px !important}@media screen and (max-width:1023px){.stk-1c8d967 .stk-block-text__text{font-size:25px !important}}<\/style><p class=\"stk-block-text__text\"><strong><span style=\"color: var(--theme-palette-color-1, #088fa8)\" class=\"stk-highlight\">Methylglyoxal is a marker of glycemic variability, meaning it allows for the assessment of the continuous fluctuations in glucose levels that can occur throughout the day.<\/span><\/strong><\/p><\/div><\/div><\/div><\/blockquote><div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div><style>.kadence-column17349_ec3f75-02 > .kt-inside-inner-col,.kadence-column17349_ec3f75-02 > .kt-inside-inner-col:before{border-top-left-radius:30px;border-top-right-radius:30px;border-bottom-right-radius:30px;border-bottom-left-radius:30px;}.kadence-column17349_ec3f75-02 > .kt-inside-inner-col{background-color:#ebebeb;}.kadence-column17349_ec3f75-02 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column17349_ec3f75-02{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column17349_ec3f75-02 kadence-column_33b0ff-ad\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id17349_b7b1a4-f2{margin-top:0px;margin-bottom:0px;}.kb-row-layout-id17349_b7b1a4-f2 > .kt-row-column-wrap{align-content:center;}:where(.kb-row-layout-id17349_b7b1a4-f2 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:center;}.kb-row-layout-id17349_b7b1a4-f2 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:0px;padding-bottom:10px;padding-left:250px;grid-template-columns:minmax(0, 80%) minmax(0, 20%);}.kb-row-layout-id17349_b7b1a4-f2{background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/02\/copertinaslide-glyco-1.png');background-size:contain;background-position:3% 100%;background-attachment:scroll;background-repeat:no-repeat;}.kb-row-layout-id17349_b7b1a4-f2 > .kt-row-layout-overlay{opacity:0.30;}.kb-row-layout-id17349_b7b1a4-f2 .kt-row-layout-bottom-sep{height:100px;}.kb-row-layout-id17349_b7b1a4-f2 .kt-row-layout-bottom-sep svg{width:100%;}.kb-row-layout-id17349_b7b1a4-f2 .kt-row-layout-bottom-sep svg{fill:#ffffff!important;}@media all and (min-width: 1025px){.kb-row-layout-id17349_b7b1a4-f2{display:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id17349_b7b1a4-f2 > .kt-row-column-wrap{padding-right:0px;padding-left:45px;grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}}@media all and (max-width: 1024px){.kb-row-layout-id17349_b7b1a4-f2{background-image:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id17349_b7b1a4-f2 [id*=\"jarallax-container-\"]{display:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id17349_b7b1a4-f2 .kt-row-layout-bottom-sep{height:px;}}@media all and (max-width: 1024px){.kb-row-layout-id17349_b7b1a4-f2 .kt-row-layout-bottom-sep svg{width:%;}}@media all and (min-width: 768px) and (max-width: 1024px){.kb-row-layout-id17349_b7b1a4-f2{display:none !important;}}@media all and (max-width: 767px){.kb-row-layout-id17349_b7b1a4-f2 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-none, 0 );row-gap:var(--global-kb-gap-none, 0 );padding-top:30px;padding-right:20px;padding-bottom:20px;padding-left:20px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id17349_b7b1a4-f2{background-image:none !important;}.kb-row-layout-id17349_b7b1a4-f2 [id*=\"jarallax-container-\"]{display:none !important;}.kb-row-layout-id17349_b7b1a4-f2 > .kt-row-layout-overlay{opacity:0.30;background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/09\/copertina.png');background-size:contain;background-position:right bottom;background-attachment:fixed;background-repeat:no-repeat;}.kb-row-layout-id17349_b7b1a4-f2 .kt-row-layout-bottom-sep{height:px;}.kb-row-layout-id17349_b7b1a4-f2 .kt-row-layout-bottom-sep svg{width:%;}.kb-row-layout-id17349_b7b1a4-f2{display:none !important;}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id17349_b7b1a4-f2 alignnone kb-v-lg-hidden kb-v-md-hidden kb-v-sm-hidden kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-layout-overlay kt-row-overlay-normal\"><\/div><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-equal kt-tab-layout-left-golden kt-mobile-layout-row kt-row-valign-middle\">\n<style>.kadence-column17349_599fba-df > .kt-inside-inner-col,.kadence-column17349_599fba-df > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column17349_599fba-df > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column17349_599fba-df{position:relative;}@media all and (max-width: 767px){.kadence-column17349_599fba-df{text-align:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column17349_599fba-df inner-column-1\"><div class=\"kt-inside-inner-col\"><div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<div class=\"wp-block-stackable-image stk-block-image has-text-align-left has-text-align-center-mobile stk-block stk-1fd7d15 alignleft\" data-block-id=\"1fd7d15\"><style>.stk-1fd7d15 .stk-img-wrapper{height:50px !important}.stk-1fd7d15 .stk-img-wrapper img{object-position:0% 50% !important;object-fit:contain !important}@media screen and (max-width:767px){.stk-1fd7d15{padding-right:60px !important;padding-left:60px !important}.stk-1fd7d15 .stk-img-wrapper img{object-fit:contain !important}}<\/style><a class=\"stk-link\" href=\"\/perme-test\/\"><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-19764\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Glyco_medical_program.webp\" width=\"1451\" height=\"418\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Glyco_medical_program.webp 1451w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Glyco_medical_program-300x86.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Glyco_medical_program-1024x295.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Glyco_medical_program-768x221.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/Glyco_medical_program-600x173.webp 600w\" sizes=\"auto, (max-width: 1451px) 100vw, 1451px\" \/><\/div><\/a><\/div>\n\n<div style=\"height:1px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p>To measure Methylglyoxal, a marker of glycemic variability, we recommend the  <strong>Glyco Medical Program<\/strong><\/p><\/div><\/div>\n\n<style>.kadence-column17349_7818a5-57 > .kt-inside-inner-col,.kadence-column17349_7818a5-57 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column17349_7818a5-57 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column17349_7818a5-57{text-align:center;}.kadence-column17349_7818a5-57{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column17349_7818a5-57\"><div class=\"kt-inside-inner-col\"><div class=\"wp-block-stackable-image stk-block-image has-text-align-center stk-block stk-af48962\" data-block-id=\"af48962\"><style>.stk-af48962{margin-bottom:0px !important}.stk-af48962 .stk-img-wrapper{width:150px !important}<\/style><figure><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-19901\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-scaled.webp\" width=\"2560\" height=\"2560\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-scaled.webp 2560w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-300x300.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-1024x1024.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-150x150.webp 150w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-768x768.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-1536x1536.webp 1536w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-2048x2048.webp 2048w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-64x64.webp 64w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-600x600.webp 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/glyco-eng-100x100.webp 100w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/div><\/figure><\/div>\n\n<div class=\"wp-block-stackable-button-group stk-block-button-group stk-block stk-5c8f60c\" data-block-id=\"5c8f60c\"><style>.stk-5c8f60c{padding-top:0px !important;padding-right:0px !important;padding-bottom:0px !important;padding-left:0px !important;margin-bottom:0px !important}<\/style><div class=\"stk-row stk-inner-blocks has-text-align-center stk-block-content stk-button-group\"><div class=\"wp-block-stackable-button stk-block-button has-text-align-center stk-block stk-0b72e9d\" data-block-id=\"0b72e9d\"><style>.stk-0b72e9d{margin-top:0px !important;margin-right:0px !important;margin-bottom:0px !important;margin-left:0px !important}<\/style><a class=\"stk-link stk-button stk--hover-effect-darken\" href=\"https:\/\/www.geklab.com\/en\/glyco-medical-program\/\"><span class=\"stk-button__inner-text\">Scopri di pi\u00f9<\/span><\/a><\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><style>.kb-row-layout-id17349_4e7411-43 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id17349_4e7411-43 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id17349_4e7411-43 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:0px;padding-bottom:0px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id17349_4e7411-43 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id17349_4e7411-43 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id17349_4e7411-43 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id17349_4e7411-43 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column17349_3f17e7-53 > .kt-inside-inner-col,.kadence-column17349_3f17e7-53 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column17349_3f17e7-53 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column17349_3f17e7-53{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column17349_3f17e7-53 inner-column-1\"><div class=\"kt-inside-inner-col\"><p>Acute fluctuations in glucose levels throughout the day, on different days, and even over longer periods can lead to multiple <strong>inflammatory conditions<\/strong> and disorders (such as reactive hypoglycemia, malabsorption, neuroinflammation, mood disorders, cardiovascular problems, etc.).<\/p>\n\n<p>The increase in methylglyoxal in the body is proportional to these blood sugar fluctuations (glucose, fructose, or other sugars).<\/p>\n\n<p>An altered relationship with sugars, without appropriate modifications, can increase the risk of developing metabolic diseases and the accumulation of oxidizing substances over the long term.<\/p>\n\n<p>Neurodegenerative diseases like Alzheimer&#8217;s, Parkinson&#8217;s, dementia, and premature aging are often induced or exacerbated by the <strong>accumulation of methylglyoxal<\/strong> and other free radicals. These conditions are on the rise in the general population.<\/p>\n\n<p>In 2010, <strong>35.6 million people<\/strong> were affected by <strong>neurodegenerative diseases<\/strong>, with estimates of this number doubling by 2030 and tripling by 2050. These alarming statistics call for early intervention and greater attention to diet.<\/p>\n\n<p>In delicate situations, such as when a woman decides to become pregnant, measuring methylglyoxal can detect <strong>gestational diabetes<\/strong> before it develops. Between 4% and 10% of women develop <strong>gestational diabetes<\/strong> during pregnancy.<\/p>\n\n<p>The GEK group participated in research and the <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32074941\/\" target=\"_blank\" rel=\"noreferrer noopener\">publication of a study in <strong>Nutrients<\/strong> in 2020<\/a><sup>4<\/sup>, which supported the use of methylglyoxal and other markers to <strong>identify sugar-induced damage early<\/strong> and prevent gestational diabetes.<\/p>\n\n<p>In this study, methylglyoxal levels were significantly higher in women with gestational diabetes compared to the control group. This molecule is a free radical that, due to its danger, is also called a <strong>glycotoxin or alarmin<\/strong>.<\/p>\n\n<p>What should be done when methylglyoxal concentrations are elevated in the body?<\/p>\n\n<p>A balanced diet should aim to allow for the slow and controlled absorption of sugars, avoiding the formation of glucose or fructose spikes that negatively impact health, energy levels, concentration, sleep quality, the ability to lose weight, and facilitate the progression of <strong>metabolic, degenerative, or inflammatory diseases<\/strong>.<\/p>\n\n<p>We know that sucrose, fructose, sweeteners, and alcohol are inducers of inflammation and weight gain. When consumed excessively, they send metabolic signals to the body that promote the accumulation of oxidizing substances like <strong>methylglyoxal<\/strong>.<\/p>\n\n<p>Humans possess a hormone (NPY) that helped the species survive in the Paleolithic era by stimulating the search for sugars. However, today, the widespread availability of sweets, excess fruit, sweeteners, and alcohol represents a potential threat to health.<\/p>\n\n<p>No food is inherently an enemy, and neither are sweets or sugar, but they should always be consumed with discernment and in accordance with individual characteristics.<\/p>\n\n<p>The measurement of glycated albumin and methylglyoxal makes it possible to detect in advance the potentially harmful effects of sugars (such as fructose, glucose, maltose, sorbitol, galactose, and others) and alcohol through the following products:<\/p>\n\n<p><a href=\"https:\/\/www.geklab.com\/en\/product\/metabolic-recaller-program\/\"><strong>Metabolic Recaller Program<\/strong>:<\/a> allows you to assess inflammation levels related to diet and sugar intake.<\/p>\n\n<p><a href=\"https:\/\/www.geklab.com\/en\/product\/perme-recaller-program\/\"><strong>PerM\u00e8 Recaller Program<\/strong>: <\/a>allows you to assess inflammation levels and identify any genetic predisposition associated with higher BAFF levels, as well as with conditions related to sugar metabolism, such as hepatic steatosis, diabetes, and overweight.<\/p>\n\n<ol style=\"margin-top:var(--wp--preset--spacing--50);margin-right:var(--wp--preset--spacing--50);margin-bottom:var(--wp--preset--spacing--50);margin-left:var(--wp--preset--spacing--50);font-size:14px\" class=\"wp-block-list\"><li>Schmidt M.I. et al., Lancet Diabetes Endocrinol. 7, 267-277 (2019). doi: 10.1016\/S2213-8587(19)30058-0.<\/li>\n\n<li>Richter B., Hemmingsen B., Metzendorf M.I. &amp; Takwoingi Y., Cochrane Database Syst. Rev. 10, CD012661 (2018). doi: 10.1002\/14651858.CD012661.pub2.<\/li>\n\n<li>Rodriguez-Segade S. et al, Acta Diabetol. (2019). doi: 10.1007\/s00592-019-01342-5.<\/li>\n\n<li>Piuri G. et al, Nutrients 2020, 12(2), 479; doi: 10.3390\/nu12020479.<\/li><\/ol>\n\n<p><em><em>By the&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/the-scientific-editorial-team\/\">Scientific Editorial Team at GEK Lab<\/a><\/em><\/em><\/p><\/div><\/div>\n<\/div><\/div><div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-11692d3\" id=\"related-articles\" data-block-id=\"11692d3\"><style>.stk-11692d3{margin-bottom:10px !important}.stk-11692d3 .stk-block-heading__text{font-size:30px !important}@media screen and (max-width:1023px){.stk-11692d3 .stk-block-heading__text{font-size:30px !important}}<\/style><h3 class=\"stk-block-heading__text has-text-align-center\">Related articles<\/h3><\/div><div class=\"wp-block-uagb-post-grid uagb-post-grid  uagb-post__image-position-top uagb-post__image-enabled uagb-block-ea6d35cb     uagb-post__items uagb-post__columns-3 is-grid uagb-post__columns-tablet-2 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However, for some&#8230;\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Methylglyoxal is a marker of glycemic variability that allows for the assessment of continuous glucose fluctuations throughout the 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is a marker of glycemic variability that allows for the assessment of continuous glucose fluctuations throughout the day.<\/p>\n","category_list":"<a href=\"https:\/\/www.geklab.com\/en\/category\/scientific-insights\/\" rel=\"category tag\">Scientific Insights<\/a>","author_info":{"name":"Marcello Granata","url":"https:\/\/www.geklab.com\/en\/author\/marcello\/"},"comments_num":"0 comments","yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Methylglyoxal: a new marker of glycemic variability<\/title>\n<meta name=\"description\" content=\"Methylglyoxal is a marker of glycemic variability that allows for the assessment of continuous glucose fluctuations throughout the day.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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