{"id":17322,"date":"2024-01-12T15:21:38","date_gmt":"2024-01-12T14:21:38","guid":{"rendered":"https:\/\/www.geklab.com\/malattie-cardiovascolari-e-infiammazione\/"},"modified":"2025-05-27T15:42:22","modified_gmt":"2025-05-27T14:42:22","slug":"cardiovascular-diseases-the-role-of-low-grade-inflammation","status":"publish","type":"post","link":"https:\/\/www.geklab.com\/en\/cardiovascular-diseases-the-role-of-low-grade-inflammation\/","title":{"rendered":"Cardiovascular diseases: the role of low-grade inflammation"},"content":{"rendered":"<div class=\"wp-block-stackable-icon-list stk-block-icon-list stk-block stk-5849285\" data-block-id=\"5849285\"><style>.stk-5849285{column-count:2 !important}.stk-5849285 ul li{list-style-image:url('data:image\/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHZpZXdCb3g9IjAgMCAxOTAgMTkwIiBzdHlsZT0iZmlsbDogIzAwMCAhaW1wb3J0YW50OyBjb2xvcjogIzAwMCAhaW1wb3J0YW50O3RyYW5zZm9ybTogcm90YXRlKGRlZykgIWltcG9ydGFudDsiPjxwb2x5Z29uIHBvaW50cz0iMTczLjgsMjguNCA2MC40LDE0MS44IDE1LjcsOTcuMiA1LjEsMTA3LjggNjAuNCwxNjMgMTg0LjQsMzkgMTczLjgsMjguNCIgZmlsbD0iIzAwMCIgc3Ryb2tlPSIjMDAwIiBzdHlsZT0iZmlsbDogcmdiKDAsIDAsIDApOyBzdHJva2U6IHJnYigwLCAwLCAwKTsiLz48L3N2Zz4=') !important}<\/style><ol><li><a href=\"#inflammation\">What is low-grade inflammation?<\/a><\/li><li><a href=\"#plaques\">Formation of atherosclerotic plaques<\/a><\/li><li><a href=\"#heart-attack\">Heart attack and stroke<\/a><\/li><li><a href=\"#arrhythmias\">Arrhythmias, tachycardia, and palpitations<\/a><\/li><li><a href=\"#sugars\">Role of sugars and related substances<\/a><\/li><li><a href=\"#measuring\">Measuring inflammation and preventing cardiovascular diseases<\/a><\/li><\/ol><\/div><figure class=\"wp-block-image alignleft size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4.jpg\" alt=\"\" class=\"wp-image-11966\" style=\"width:464px;height:auto\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4.jpg 750w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4-300x200.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4-600x400.jpg 600w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/><\/figure><p>The term \u201clow-grade inflammation\u201d may sound somewhat reassuring, but it\u2019s actually a key concept that can significantly impact the health of our hearts in surprising ways.<\/p><p>In this article, we\u2019ll explore the link between low-grade inflammation and cardiovascular diseases, seeking to understand how these processes influence the well-being of our cardiovascular system.<\/p><div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-bd645a6\" id=\"inflammation\" data-block-id=\"bd645a6\"><style>.stk-bd645a6{margin-bottom:15px !important}<\/style><h2 class=\"stk-block-heading__text stk-block-heading--use-theme-margins\"><strong><strong>What is low-grade inflammation?<\/strong><\/strong><\/h2><\/div><p>Inflammation is a natural response of our body to injuries, trauma, or infections.<\/p><p>Typically, this response is temporary: inflammatory chemicals are released to attract immune system cells to eliminate the harmful agent and repair tissues.<\/p><div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div><blockquote class=\"wp-block-stackable-blockquote stk-block-blockquote stk-block stk-8339d85 is-style-simple\" data-v=\"2\" data-block-id=\"8339d85\"><style>.stk-8339d85{margin-bottom:0px !important}<\/style><div class=\"has-text-align-left stk-block-blockquote__content stk-container stk-8339d85-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks\"><div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-3ce51f5\" data-block-id=\"3ce51f5\"><style>.stk-3ce51f5{left:-50px !important;position:absolute !important;opacity:0.2 !important}.stk-3ce51f5 .stk--svg-wrapper .stk--inner-svg svg:last-child{height:100px !important;width:100px !important}.stk-3ce51f5 .stk--svg-wrapper .stk--inner-svg svg:last-child,.stk-3ce51f5 .stk--svg-wrapper .stk--inner-svg svg:last-child :is(g,path,rect,polygon,ellipse){fill:var(--theme-palette-color-1,#088fa8) !important}@media screen and (max-width:767px){.stk-3ce51f5{left:0px !important}}<\/style><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><linearGradient id=\"linear-gradient-3ce51f5\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-3-ce-51-f-5-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-3-ce-51-f-5-color-2)\"><\/stop><\/linearGradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 50 50\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M22.3 30.5c0 6-4.8 10.8-10.8 10.8-2.3 0-4.5-.8-6.3-2-.9-.6-1.8-1.4-2.5-2.4-1.8-2.4-2.7-5.4-2.7-9 0-4.5 1.3-8.5 4-11.9 2.7-3.4 6.4-5.8 11.1-7.3v2.8c-2.7 2.2-4.4 5-4.9 8.3.4-.1.9-.1 1.3-.1 6-.1 10.8 4.8 10.8 10.8zm16.9-10.9c-.5 0-.9 0-1.3.1.5-3.3 2.2-6.1 4.9-8.3V8.7c-4.7 1.4-8.4 3.9-11.1 7.3-2.7 3.4-4 7.4-4 11.9 0 3.6.9 6.6 2.7 9 .8 1 1.6 1.8 2.5 2.4 1.8 1.3 3.9 2 6.3 2 6 0 10.8-4.8 10.8-10.8 0-6-4.8-10.9-10.8-10.9z\"><\/path><\/svg><\/div><\/span><\/div>\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-1c8d967\" data-block-id=\"1c8d967\"><style>.stk-1c8d967 .stk-block-text__text{font-size:25px !important}@media screen and (max-width:1023px){.stk-1c8d967 .stk-block-text__text{font-size:25px !important}}<\/style><p class=\"stk-block-text__text\"><strong><span style=\"color: var(--theme-palette-color-1, #088fa8);\" class=\"stk-highlight\"><strong><span style=\"color: var(--theme-palette-color-1, #088fa8);\" class=\"stk-highlight\"><strong><strong>The causes of low-grade inflammation are not isolated but often interconnected. For instance, an unbalanced diet can lead to metabolic dysfunctions (such as obesity, type 2 diabetes), stress, and imbalances in the microbiota, all contributing to chronic inflammation<\/strong><\/strong>. <\/span><\/strong><\/span><\/strong><\/p><\/div><\/div><\/div><\/blockquote><div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div><style>.kadence-column17322_8d5155-ce > .kt-inside-inner-col,.kadence-column17322_8d5155-ce > .kt-inside-inner-col:before{border-top-left-radius:30px;border-top-right-radius:30px;border-bottom-right-radius:30px;border-bottom-left-radius:30px;}.kadence-column17322_8d5155-ce > .kt-inside-inner-col{background-color:#ebebeb;}.kadence-column17322_8d5155-ce > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column17322_8d5155-ce{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column17322_8d5155-ce kadence-column_33b0ff-ad\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id17322_32d645-21{margin-top:0px;margin-bottom:0px;}.kb-row-layout-id17322_32d645-21 > .kt-row-column-wrap{align-content:center;}:where(.kb-row-layout-id17322_32d645-21 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:center;}.kb-row-layout-id17322_32d645-21 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:0px;padding-bottom:10px;padding-left:250px;grid-template-columns:minmax(0, 80%) minmax(0, 20%);}.kb-row-layout-id17322_32d645-21{background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/06\/slider4-copia-1.png');background-size:contain;background-position:3% 100%;background-attachment:scroll;background-repeat:no-repeat;}.kb-row-layout-id17322_32d645-21 > .kt-row-layout-overlay{opacity:0.30;}.kb-row-layout-id17322_32d645-21 .kt-row-layout-bottom-sep{height:100px;}.kb-row-layout-id17322_32d645-21 .kt-row-layout-bottom-sep svg{width:100%;}.kb-row-layout-id17322_32d645-21 .kt-row-layout-bottom-sep svg{fill:#ffffff!important;}@media all and (max-width: 1024px){.kb-row-layout-id17322_32d645-21 > .kt-row-column-wrap{padding-right:0px;padding-left:45px;grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}}@media all and (max-width: 1024px){.kb-row-layout-id17322_32d645-21{background-image:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id17322_32d645-21 [id*=\"jarallax-container-\"]{display:none !important;}}@media all and (max-width: 1024px){.kb-row-layout-id17322_32d645-21 .kt-row-layout-bottom-sep{height:px;}}@media all and (max-width: 1024px){.kb-row-layout-id17322_32d645-21 .kt-row-layout-bottom-sep svg{width:%;}}@media all and (max-width: 767px){.kb-row-layout-id17322_32d645-21 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-none, 0 );row-gap:var(--global-kb-gap-none, 0 );padding-top:30px;padding-right:20px;padding-bottom:20px;padding-left:20px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id17322_32d645-21{background-image:none !important;}.kb-row-layout-id17322_32d645-21 [id*=\"jarallax-container-\"]{display:none !important;}.kb-row-layout-id17322_32d645-21 > .kt-row-layout-overlay{opacity:0.30;background-image:url('https:\/\/www.geklab.com\/wp-content\/uploads\/2022\/09\/copertina.png');background-size:contain;background-position:right bottom;background-attachment:fixed;background-repeat:no-repeat;}.kb-row-layout-id17322_32d645-21 .kt-row-layout-bottom-sep{height:px;}.kb-row-layout-id17322_32d645-21 .kt-row-layout-bottom-sep svg{width:%;}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id17322_32d645-21 alignnone kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-layout-overlay kt-row-overlay-normal\"><\/div><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-equal kt-tab-layout-left-golden kt-mobile-layout-row kt-row-valign-middle\">\n<style>.kadence-column17322_ac8bc6-73 > .kt-inside-inner-col,.kadence-column17322_ac8bc6-73 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column17322_ac8bc6-73 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column17322_ac8bc6-73{position:relative;}@media all and (max-width: 767px){.kadence-column17322_ac8bc6-73{text-align:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column17322_ac8bc6-73 inner-column-1\"><div class=\"kt-inside-inner-col\"><div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<div class=\"wp-block-stackable-image stk-block-image has-text-align-left has-text-align-center-mobile stk-block stk-1fd7d15 alignleft\" data-block-id=\"1fd7d15\"><style>.stk-1fd7d15 .stk-img-wrapper{height:50px !important}.stk-1fd7d15 .stk-img-wrapper img{object-position:0% 50% !important;object-fit:contain !important}@media screen and (max-width:767px){.stk-1fd7d15{padding-right:60px !important;padding-left:60px !important}.stk-1fd7d15 .stk-img-wrapper img{object-fit:contain !important}}<\/style><a class=\"stk-link\" href=\"\/perme-test\/\"><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-19755\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program.webp\" width=\"1576\" height=\"418\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program.webp 1576w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-300x80.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-1024x272.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-768x204.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-1536x407.webp 1536w, https:\/\/www.geklab.com\/wp-content\/uploads\/2025\/02\/PerMe_medical_program-600x159.webp 600w\" sizes=\"auto, (max-width: 1576px) 100vw, 1576px\" \/><\/div><\/a><\/div>\n\n<div style=\"height:1px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p>To establish a personalized diet and&nbsp;<strong>prevent cardiovascular diseases<\/strong>, we recommend taking the<strong> PerM\u00e8<\/strong> <strong>Medical Program<\/strong><\/p><\/div><\/div>\n\n<style>.kadence-column17322_d5ab5f-3f > .kt-inside-inner-col,.kadence-column17322_d5ab5f-3f > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column17322_d5ab5f-3f > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column17322_d5ab5f-3f{text-align:center;}.kadence-column17322_d5ab5f-3f{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column17322_d5ab5f-3f\"><div class=\"kt-inside-inner-col\"><div class=\"wp-block-stackable-image stk-block-image has-text-align-center stk-block stk-af48962\" data-block-id=\"af48962\"><style>.stk-af48962{margin-bottom:0px !important}.stk-af48962 .stk-img-wrapper{width:150px !important}<\/style><figure><div class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-20166\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-scaled.webp\" width=\"2560\" height=\"2560\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-scaled.webp 2560w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-300x300.webp 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-1024x1024.webp 1024w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-150x150.webp 150w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-768x768.webp 768w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-1536x1536.webp 1536w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-2048x2048.webp 2048w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-64x64.webp 64w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-600x600.webp 600w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/03\/perme-eng-100x100.webp 100w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/div><\/figure><\/div>\n\n<div class=\"wp-block-stackable-button-group stk-block-button-group stk-block stk-5c8f60c\" data-block-id=\"5c8f60c\"><style>.stk-5c8f60c{padding-top:0px !important;padding-right:0px !important;padding-bottom:0px !important;padding-left:0px !important;margin-bottom:0px !important}<\/style><div class=\"stk-row stk-inner-blocks has-text-align-center stk-block-content stk-button-group\"><div class=\"wp-block-stackable-button stk-block-button has-text-align-center stk-block stk-0b72e9d\" data-block-id=\"0b72e9d\"><style>.stk-0b72e9d{margin-top:0px !important;margin-right:0px !important;margin-bottom:0px !important;margin-left:0px !important}<\/style><a class=\"stk-link stk-button stk--hover-effect-darken\" href=\"https:\/\/www.geklab.com\/en\/perme-medical-program\/\"><span class=\"stk-button__inner-text\">See more<\/span><\/a><\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><style>.kb-row-layout-id17322_801253-fd > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id17322_801253-fd > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id17322_801253-fd > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id17322_801253-fd > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id17322_801253-fd > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id17322_801253-fd > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id17322_801253-fd alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column17322_92031e-5b > .kt-inside-inner-col,.kadence-column17322_92031e-5b > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column17322_92031e-5b > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column17322_92031e-5b{position:relative;}<\/style>\n<div class=\"wp-block-kadence-column kadence-column17322_92031e-5b inner-column-1\"><div class=\"kt-inside-inner-col\"><p>However, low-grade inflammation is different: it\u2019s a long-term response that can persist for weeks, months, or even years. It can be caused by factors such as unhealthy lifestyles, persistent infections, imbalances in gut bacterial flora, stress, immune system dysfunctions,&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/the-rotation-diet-how-it-works-and-why\/\">repetitive eating patterns<\/a>, and excessive glycation. These causes are not isolated but often interconnected. For example, an unbalanced diet can lead to metabolic dysfunctions (such as obesity or&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/diabetes-and-hyperglycemia-an-overview\/\">type 2 diabetes<\/a>), stress, and imbalances in the microbiota, contributing to chronic inflammation. It\u2019s a more subtle and insidious form of inflammation that can develop at the cellular level without obvious symptoms.<\/p>\n\n<p>Low-grade inflammation plays a crucial role in the development of cardiovascular diseases: let\u2019s see how.<\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-3a427d1\" id=\"plaques\" data-block-id=\"3a427d1\"><style>.stk-3a427d1{margin-bottom:15px !important}<\/style><h2 class=\"stk-block-heading__text stk-block-heading--use-theme-margins\"><strong><strong><strong>Formation of atherosclerotic plaques<\/strong><\/strong><\/strong><\/h2><\/div>\n\n<p>In conditions of inflammation, the endothelial cells lining the walls of arteries can become more permeable and \u201cwelcoming\u201d to lipoproteins, especially low-density lipoproteins (LDL), commonly known as \u201cbad cholesterol.\u201d The accumulation of LDL in the artery walls is the first step toward plaque formation.<\/p>\n\n<p>Subsequently, immune system cells also accumulate in inflamed areas. This process can lead to the formation of deposits that make arterial walls thicker and less elastic. Over time, plaques can grow,&nbsp;<strong>partially or completely obstructing blood flow<\/strong>.<\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-5fced32\" id=\"heart-attack\" data-block-id=\"5fced32\"><style>.stk-5fced32{margin-bottom:16px !important}<\/style><h2 class=\"stk-block-heading__text stk-block-heading--use-theme-margins\"><strong><strong>Heart attack and stroke<\/strong><\/strong><\/h2><\/div>\n\n<p id=\"aritmie\">Atherosclerotic plaques can become unstable and prone to rupture over time. When a plaque ruptures, it can cause the formation of a blood clot on the damaged surface. This clot can completely block a coronary artery, leading to a&nbsp;<strong>heart attack<\/strong>, or travel through the vascular system to the brain, causing a <strong>stroke<\/strong>. In this case as well,&nbsp;<strong>inflammation plays a key role<\/strong>&nbsp;in plaque destabilization, through various mechanisms (mainly by degrading some structural components of the plaque, such as collagen).<\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-9fa746a\" id=\"arrhythmias\" data-block-id=\"9fa746a\"><style>.stk-9fa746a{margin-bottom:14px !important}<\/style><h2 class=\"stk-block-heading__text stk-block-heading--use-theme-margins\"><strong><strong>Arrhythmias, tachycardia, and palpitations<\/strong><\/strong><\/h2><\/div>\n\n<p>Recent research has allowed the correlation of cardiac arrhythmias (whether it be palpitations, atrial fibrillation, tachyarrhythmias, or extrasystoles) with inflammatory cytokines such as TNF-alpha,&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/baff-a-multitasking-molecule-why-measure-it-and-how-to-deal-with-it\/\">BAFF<\/a>, IL6, and others.<\/p>\n\n<p>These effects go beyond the direct stimuli exerted by certain foods or beverages, such as caffeine or alcohol.<\/p>\n\n<p>Some phenomena of cardiac rhythm disturbance, not caused by electrical or anatomical abnormalities of the heart, may instead depend on an induced inflammatory stimulus at the intestinal level, triggered by food intake.<\/p>\n\n<p>This means that persistent arrhythmia, in the absence of specific alterations in heart muscle, could result from&nbsp;<strong>daily and repeated consumption<\/strong>&nbsp;of bread or any other common food.<\/p>\n\n<p>Assessing the level of inflammation and understanding an individual\u2019s dietary profile can contribute (through an&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/the-rotation-diet-how-it-works-and-why\/\">appropriate diet<\/a>) to the healing process or improvement of such conditions.<\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-bcb37a9\" id=\"sugars\" data-block-id=\"bcb37a9\"><style>.stk-bcb37a9{margin-bottom:14px !important}<\/style><h2 class=\"stk-block-heading__text stk-block-heading--use-theme-margins\"><strong><strong>Role of sugars and related substances<\/strong><\/strong><\/h2><\/div>\n\n<p>Excessive consumption of sugars and related substances (including excessive fruit intake, carbohydrate-heavy meals, as well as alcohol and sweeteners) can lead to an increase in various free radicals, including Methylglyoxal. When this substance binds to \u201cgood\u201d cholesterol, it causes a decrease in its levels, resulting in an increase in \u201cbad\u201d cholesterol and an elevation in cardiovascular risk. Methylglyoxal also has a high inflammatory potential and generates oxidative stress in cells, including those of cardiac and vascular tissues.<\/p>\n\n<p><strong>Individually excessive sugar consumption<\/strong>&nbsp;can also cause&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/insulin-resistance-sugar-induced-inflammation-and-weight-loss\/\">insulin resistance<\/a>, which, in addition to being associated with increased inflammation, can contribute to the development of&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/diabetes-and-hyperglycemia-an-overview\/\">type 2 diabetes<\/a>.<\/p>\n\n<p>Systemic inflammation associated with diabetes can also damage arterial walls, contributing to plaque formation and occlusions, following the mechanisms we have already explained. High blood sugar levels also cause stiffness in the blood vessels and affect their ability to regulate blood flow, increasing the&nbsp;<strong>risk of hypertension<\/strong>.<\/p>\n\n<p>Similar to its effect on muscles (as athletes are well aware), Methylglyoxal reduces energy production from mitochondria, and when considering the reduced strength of the heart, one might think of heart failure or circulatory insufficiency. A properly tailored diet can always improve heart function.<\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-3ba7c69\" id=\"measuring\" data-block-id=\"3ba7c69\"><style>.stk-3ba7c69{margin-bottom:15px !important}<\/style><h2 class=\"stk-block-heading__text stk-block-heading--use-theme-margins\"><strong><strong>Measuring inflammation and preventing cardiovascular diseases<\/strong><\/strong><\/h2><\/div>\n\n<p>Considering all that has been explained so far,&nbsp;<strong>understanding one\u2019s inflammation levels<\/strong>&nbsp;increasingly gains value from the perspective of preventing cardiovascular diseases. Conducting a&nbsp;<strong><a href=\"https:\/\/www.geklab.com\/en\/perme-medical-program\/\">PerM\u00e8 Medical Program<\/a><\/strong>&nbsp;allows for the measurement of both inflammatory cytokines such as&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/baff-a-multitasking-molecule-why-measure-it-and-how-to-deal-with-it\/\">BAFF<\/a>&nbsp;and PAF, as well as highly sophisticated indicators of sugar-related inflammation such as Methylglyoxal and Glycated Albumin, which also provide valuable information on the likelihood of developing&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/diabetes-and-hyperglycemia-an-overview\/\">type 2 diabetes<\/a>.<\/p>\n\n<p>Measuring these substances and following the advice provided in the <strong><a href=\"https:\/\/www.geklab.com\/en\/perme-medical-program\/\">PerM\u00e8 Medical Program<\/a><\/strong> allows for the immediate implementation of personalized nutritional choices that help maintain one\u2019s well-being and cardiovascular health.<\/p>\n\n<p>By controlling inflammation, reducing fat mass, and managing glycemic variability, the foundation is laid for staying healthy and fit in the long term.<\/p>\n\n<p><em>By the&nbsp;<a href=\"https:\/\/www.geklab.com\/en\/the-scientific-editorial-team\/\">Scientific Editorial Team at GEK Lab<\/a><\/em><\/p>\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-11692d3\" id=\"related-articles\" data-block-id=\"11692d3\"><style>.stk-11692d3{margin-bottom:10px !important}.stk-11692d3 .stk-block-heading__text{font-size:30px !important}@media screen and (max-width:1023px){.stk-11692d3 .stk-block-heading__text{font-size:30px !important}}<\/style><h3 class=\"stk-block-heading__text has-text-align-center\">Related articles<\/h3><\/div>\n\n<div class=\"wp-block-uagb-post-grid uagb-post-grid  uagb-post__image-position-top uagb-post__image-enabled uagb-block-ea6d35cb     uagb-post__items uagb-post__columns-3 is-grid uagb-post__columns-tablet-2 uagb-post__columns-mobile-1 uagb-post__equal-height\" data-total=\"1\" style=\"\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"uagb-post__inner-wrap\">\t\t\t\t\t\t\t\t<div class='uagb-post__image'>\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/high-blood-pressure-and-chronic-inflammation-how-they-interact-and-how-to-intervene\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\" class='uagb-image-ratio-inherit'><img loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/10\/Ipertensione-meglio-ridurre-l-infiammazione_articleimage-5.jpg\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/10\/Ipertensione-meglio-ridurre-l-infiammazione_articleimage-5.jpg 750w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/10\/Ipertensione-meglio-ridurre-l-infiammazione_articleimage-5-300x200.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/10\/Ipertensione-meglio-ridurre-l-infiammazione_articleimage-5-600x400.jpg 600w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/>\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<h5 class=\"uagb-post__title uagb-post__text\">\n\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/high-blood-pressure-and-chronic-inflammation-how-they-interact-and-how-to-intervene\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\">High blood pressure and chronic inflammation: how they interact and how to intervene<\/a>\n\t\t\t<\/h5>\n\t\t\t\t\t\t<div class='uagb-post__text uagb-post-grid-byline'>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class='uagb-post__text uagb-post__excerpt'>\n\t\t\t\t\tHypertension, commonly referred to as &#8220;high blood pressure,&#8221; is one of the most widespread and&#8230;\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"uagb-post__inner-wrap\">\t\t\t\t\t\t\t\t<div class='uagb-post__image'>\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/cardiovascular-diseases-prevention-on-your-plate\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\" class='uagb-image-ratio-inherit'><img loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/La-dieta-che-aiuta-il-cardiologo_articleimage-5.jpg\" class=\"attachment-large size-large\" alt=\"alimentazione e malattie cardiovascolari\" srcset=\"https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/La-dieta-che-aiuta-il-cardiologo_articleimage-5.jpg 750w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/La-dieta-che-aiuta-il-cardiologo_articleimage-5-300x200.jpg 300w, https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/La-dieta-che-aiuta-il-cardiologo_articleimage-5-600x400.jpg 600w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/>\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<h5 class=\"uagb-post__title uagb-post__text\">\n\t\t\t\t<a href=\"https:\/\/www.geklab.com\/en\/cardiovascular-diseases-prevention-on-your-plate\/\" target=\"_self\" rel=\"bookmark noopener noreferrer\">Cardiovascular diseases: prevention on your plate<\/a>\n\t\t\t<\/h5>\n\t\t\t\t\t\t<div class='uagb-post__text uagb-post-grid-byline'>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class='uagb-post__text uagb-post__excerpt'>\n\t\t\t\t\tNutrition can play a crucial role in preventing and counteracting inflammatory conditions and, consequently, cardiovascular&#8230;\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div><\/div>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The term &#8220;low-grade inflammation&#8221; may sound somewhat reassuring, but it&#8217;s actually a key concept that can impact the health of our hearts in surprising ways. This article delves into the connection between low-grade inflammation and cardiovascular diseases, seeking to understand how these processes affect the well-being of our cardiovascular system.<\/p>\n","protected":false},"author":2,"featured_media":11967,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[305],"tags":[204,243,203,206,242,247,334,353,309,211,246],"class_list":["post-17322","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-conditions","tag-atherosclerosis","tag-cardiovascular-diseases","tag-cholesterol","tag-diabetes","tag-heart","tag-heart-attack","tag-infiammazione-en","tag-infiammazione-da-zuccheri-en","tag-inflammation-en","tag-perme-medical-program","tag-stroke"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":6}},"featured_image_urls":{"full":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4.jpg",750,500,false],"thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4-150x150.jpg",150,150,true],"medium":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4-300x200.jpg",300,200,true],"medium_large":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4.jpg",750,500,false],"large":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4.jpg",750,500,false],"1536x1536":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4.jpg",750,500,false],"2048x2048":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4.jpg",750,500,false],"xs-thumb":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4.jpg",64,43,false],"woocommerce_archive_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4-300x400.jpg",300,400,true],"woocommerce_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4-300x400.jpg",300,400,true],"woocommerce_single":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4-600x400.jpg",600,400,true],"woocommerce_gallery_thumbnail":["https:\/\/www.geklab.com\/wp-content\/uploads\/2024\/01\/Malattie-cardiovascolari-e-rischio-cardiaco-e-se-i-grassi-non-c-entrassero-nulla_articleimage-4-100x100.jpg",50,50,true]},"post_excerpt_stackable":"<p>The term &#8220;low-grade inflammation&#8221; may sound somewhat reassuring, but it&#8217;s actually a key concept that can impact the health of our hearts in surprising ways. This article delves into the connection between low-grade inflammation and cardiovascular diseases, seeking to understand how these processes affect the well-being of our cardiovascular system.<\/p>\n","category_list":"<a href=\"https:\/\/www.geklab.com\/en\/category\/conditions\/\" rel=\"category tag\">Conditions<\/a>","author_info":{"name":"Marcello Granata","url":"https:\/\/www.geklab.com\/en\/author\/marcello\/"},"comments_num":"0 comments","yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cardiovascular diseases: the role of low-grade inflammation<\/title>\n<meta name=\"description\" content=\"Low-grade inflammation plays a crucial role in the development of cardiovascular diseases affecting our well-being and cardiovascular health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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